The significance and regulatory mechanisms of innate immune cells in the development of sepsis
YY Luan, N Dong, M Xie, XZ Xiao… - Journal of Interferon & …, 2014 - liebertpub.com
Sepsis with subsequent multiple organ dysfunction is a pronounced systemic inflammatory
response to concealed or known infection and is a leading cause of death in intensive care …
response to concealed or known infection and is a leading cause of death in intensive care …
Inflammation and cell death of the innate and adaptive immune system during sepsis
C Nedeva - Biomolecules, 2021 - mdpi.com
Sepsis is a life-threatening medical condition that occurs when the host has an uncontrolled
or abnormal immune response to overwhelming infection. It is now widely accepted that …
or abnormal immune response to overwhelming infection. It is now widely accepted that …
The immune system regulation in sepsis: from innate to adaptive
Y Qiu, G Tu, M Ju, C Yang, Z Luo - Current Protein and Peptide …, 2019 - ingentaconnect.com
Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of
a systemic inflammatory response syndrome. The activation and regulation of the immune …
a systemic inflammatory response syndrome. The activation and regulation of the immune …
Role of cellular events in the pathophysiology of sepsis
Introduction Sepsis is a dysregulated host immune response due to an uncontrolled
infection. It is a leading cause of mortality in adult intensive care units globally. When the …
infection. It is a leading cause of mortality in adult intensive care units globally. When the …
Innate immunity in sepsis pathogenesis and its modulation: new immunomodulatory targets revealed
V Kumar, A Sharma - Journal of chemotherapy, 2008 - Taylor & Francis
Sepsis is complex clinical manifestation of an organism's overwhelming and unregulated
immune response to infection. Despite more than 25 years of extensive re search, sepsis …
immune response to infection. Despite more than 25 years of extensive re search, sepsis …
Current trends in inflammatory and immunomodulatory mediators in sepsis
Review on sepsis mediators, and roles in innate and adaptive immune systems, as well as
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
Innate lymphoid cells: Potent early mediators of the host immune response during sepsis
M Theertha, S Sanju, VV Priya, P Jain… - Cellular & molecular …, 2020 - nature.com
Sepsis is a life-threatening syndrome caused by a dysregulated host response to infection,
resulting in very high mortality. Dysfunction of the tightly regulated immune response occurs …
resulting in very high mortality. Dysfunction of the tightly regulated immune response occurs …
In search of a cure for sepsis: taming the monster in critical care medicine
In spite of over half a century of research, sepsis still constitutes a major problem in health
care delivery. Although advances in research have significantly increased our knowledge of …
care delivery. Although advances in research have significantly increased our knowledge of …
Sepsis: rethinking the approach to clinical research
JC Marshall - Journal of Leucocyte Biology, 2008 - academic.oup.com
The clinical syndrome of sepsis encompasses a highly heterogeneous group of clinical
disorders, varying with respect to the site, bacteriology, and even presence of infection and …
disorders, varying with respect to the site, bacteriology, and even presence of infection and …
[HTML][HTML] Sepsis and nosocomial infection: patient characteristics, mechanisms, and modulation
SJ Denstaedt, BH Singer, TJ Standiford - Frontiers in Immunology, 2018 - frontiersin.org
Sepsis is a leading cause of death worldwide. After initial trials modulating the
hyperinflammatory phase of sepsis failed, generations of researchers have focused on …
hyperinflammatory phase of sepsis failed, generations of researchers have focused on …