[HTML][HTML] Leveraging the fragment length of circulating tumour DNA to improve molecular profiling of solid tumour malignancies with next-generation sequencing: a …
HR Underhill - Molecular diagnosis & therapy, 2021 - Springer
Circulating cell-free DNA (ccfDNA) has emerged as a promising diagnostic tool in oncology.
Identification of tumour-derived ccfDNA (ie circulating tumour DNA [ctDNA]) provides non …
Identification of tumour-derived ccfDNA (ie circulating tumour DNA [ctDNA]) provides non …
[HTML][HTML] Circulating tumor DNA: current challenges for clinical utility
DK Dang, BH Park - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
Cancer cells shed naked DNA molecules into the circulation. This circulating tumor DNA
(ctDNA) has become the predominant analyte for liquid biopsies to understand the …
(ctDNA) has become the predominant analyte for liquid biopsies to understand the …
Enhanced detection of circulating tumor DNA by fragment size analysis
F Mouliere, D Chandrananda, AM Piskorz… - Science translational …, 2018 - science.org
Existing methods to improve detection of circulating tumor DNA (ctDNA) have focused on
genomic alterations but have rarely considered the biological properties of plasma cell-free …
genomic alterations but have rarely considered the biological properties of plasma cell-free …
Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoring
Y Chang, B Tolani, X Nie, X Zhi, M Hu… - Therapeutics and clinical …, 2017 - Taylor & Francis
Circulating cell-free DNA (cfDNA) released by tumor cells, termed ctDNA, closely reflects the
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
Diagnostic and prognostic value of circulating tumor-related DNA in cancer patients
DM Marzese, H Hirose, DSB Hoon - Expert review of molecular …, 2013 - Taylor & Francis
Qualitative and quantitative analysis of circulating cell-free DNA (cfDNA) is an emerging non-
invasive blood biomarker utilized to assess tumor progression and to evaluate prognosis …
invasive blood biomarker utilized to assess tumor progression and to evaluate prognosis …
[HTML][HTML] Integrating circulating-free DNA (cfDNA) analysis into clinical practice: opportunities and challenges
M Garcia-Pardo, M Makarem, JJN Li, D Kelly… - British Journal of …, 2022 - nature.com
In the current era of precision medicine, the identification of genomic alterations has
revolutionised the management of patients with solid tumours. Recent advances in the …
revolutionised the management of patients with solid tumours. Recent advances in the …
Potential clinical utility of ultrasensitive circulating tumor DNA detection with CAPP-Seq
Tumors continually shed DNA into the circulation, where it can be noninvasively accessed.
The ability to accurately detect circulating tumor DNA (ctDNA) could significantly impact the …
The ability to accurately detect circulating tumor DNA (ctDNA) could significantly impact the …
Liquid biopsy: unlocking the potentials of cell-free DNA
Circulating tumor DNA (ctDNA) has garnered much excitement over the past few years for its
potential clinical utility as a surrogate for tumor biopsies in early cancer detection and …
potential clinical utility as a surrogate for tumor biopsies in early cancer detection and …
Technical progress in circulating tumor DNA analysis using next generation sequencing
Y Bai, Z Wang, Z Liu, G Liang, W Gu, Q Ge - Molecular and cellular probes, 2020 - Elsevier
Circulating tumor DNA (ctDNA) is tumor-derived, fragmented DNA that circulates freely in
body fluids, predominantly in the peripheral blood. Recently, ctDNA analysis has been …
body fluids, predominantly in the peripheral blood. Recently, ctDNA analysis has been …
[HTML][HTML] Circulating tumor DNA in precision oncology and its applications in colorectal cancer
MF Arisi, E Dotan, SV Fernandez - International Journal of Molecular …, 2022 - mdpi.com
Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …
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