[PDF][PDF] Is water the best solvent for biocatalysis

D Holtmann, F Hollmann - Mol. Catal, 2022 - pure.tudelft.nl
At first glance, the answer is quite obvious: water is the perfect solvent for biocatalytic
reactions. Life depends on water, living cells contain approx. 75% of water, most enzymes …

Enzyme mediated C C bond formation

WD Fessner - Current opinion in chemical biology, 1998 - Elsevier
A number of significant biocatalysts have been investigated over the past year to improve
accessibility, functional knowledge and use in developing synthetic applications. In …

Biological concepts for catalysis and reactivity: empowering bioinspiration

A Das, C Hessin, Y Ren… - Chemical Society Reviews, 2020 - pubs.rsc.org
Biological systems provide attractive reactivity blueprints for the design of challenging
chemical transformations. Emulating the operating mode of natural systems may however …

Recent advances in developing chemoenzymatic processes for active pharmaceutical ingredients

Junhua, L Zhao, N Ran - Organic process research & development, 2007 - ACS Publications
Biocatalysis is becoming a transformational technology for chemical synthesis as a result of
recent advances in large-scale DNA sequencing, structural biology, protein expression, high …

Extending the application of biocatalysis to meet the challenges of drug development

PN Devine, RM Howard, R Kumar… - Nature Reviews …, 2018 - nature.com
The pharmaceutical industry, driven by an increasing need to deliver new and more effective
medicines to patients, is increasingly turning to the use of engineered biocatalysts for both …

Biocatalysis as key to sustainable industrial chemistry

AR Alcántara, P Domínguez de María… - …, 2022 - Wiley Online Library
The role and power of biocatalysis in sustainable chemistry has been continuously brought
forward step by step to its present outstanding position. The problem‐solving capabilities of …

[图书][B] Biocatalysis in organic synthesis: The retrosynthesis approach

NJ Turner, L Humphreys - 2018 - books.google.com
The application of biocatalysis in organic synthesis is rapidly gaining popularity amongst
chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of …

[图书][B] Enzyme catalysis in organic synthesis, 3 volume set

K Drauz, H Gröger, O May - 2012 - books.google.com
This comprehensive three-volume set is the standard reference in the field of organic
synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly …

Biocatalytic promiscuity

MS Humble, P Berglund - European Journal of Organic …, 2011 - Wiley Online Library
Enzymes are attractive catalysts because of their promiscuity and their ability to perform
highly regio‐, chemo‐and stereoselective transformations. Enzyme promiscuity allows …

[HTML][HTML] Novel carbon–carbon bond formations for biocatalysis

V Resch, JH Schrittwieser, E Siirola, W Kroutil - Current opinion in …, 2011 - Elsevier
Carbon–carbon bond formation is the key transformation in organic synthesis to set up the
carbon backbone of organic molecules. However, only a limited number of enzymatic C–C …