Methods to Illuminate the Role of Salmonella Effector Proteins during Infection: A Review

AM Young, AE Palmer - Frontiers in Cellular and Infection …, 2017 - frontiersin.org
Intracellular bacterial pathogens like Salmonella enterica use secretion systems, such as the
Type III Secretion System, to deliver virulence factors into host cells in order to invade and …

Integrative structural analysis of the type III secretion system needle complex from Shigella flexneri

L Flacht, M Lunelli, K Kaszuba, ZA Chen… - Protein …, 2023 - Wiley Online Library
The type III secretion system (T3SS) is a large, transmembrane protein machinery used by
various pathogenic gram‐negative bacteria to transport virulence factors into the host cell …

Salmonella enterica Serovar Typhimurium Pathogenicity Island 1-Encoded Type III Secretion System Translocases Mediate Intimate Attachment to Nonphagocytic …

M Lara-Tejero, JE Galán - Infection and immunity, 2009 - Am Soc Microbiol
Delivery of bacterial proteins into mammalian cells by type III secretion systems (TTSS) is
thought to require the intimate association of bacteria with target cells. The molecular bases …

[HTML][HTML] Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism

TRS Matthews-Palmer, N Gonzalez-Rodriguez… - Journal of structural …, 2021 - Elsevier
Bacterial type III secretion systems assemble the axial structures of both injectisomes and
flagella. Injectisome type III secretion systems subsequently secrete effector proteins through …

Quantification of real-time Salmonella effector type III secretion kinetics reveals differential secretion rates for SopE2 and SptP

SB VanEngelenburg, AE Palmer - Chemistry & biology, 2008 - cell.com
Gram-negative pathogenic bacteria such as Salmonella utilize the type III secretion system
to inject bacterial effector proteins into a host cell. Upon entry, these effectors bind …

A Substrate-Fusion Protein Is Trapped inside the Type III Secretion System Channel in Shigella flexneri

K Dohlich, AB Zumsteg, C Goosmann, M Kolbe - PLoS pathogens, 2014 - journals.plos.org
The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative
bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a …

Assembly and function of type III secretory systems

GR Cornelis, F Van Gijsegem - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Type III secretion systems allow Yersinia spp., Salmonella spp., Shigella spp.,
Bordetella spp., and Pseudomonas aeruginosa and enteropathogenic Escherichia coli …

Hierarchical Effector Protein Transport by the Salmonella Typhimurium SPI-1 Type III Secretion System

B Winnen, MC Schlumberger, A Sturm, K Schüpbach… - PloS one, 2008 - journals.plos.org
Background Type III secretion systems (TTSS) are employed by numerous pathogenic and
symbiotic bacteria to inject a cocktail of different “effector proteins” into host cells. These …

Salmonella T3SSs: successful mission of the secret (ion) agents

TP Moest, S Méresse - Current opinion in microbiology, 2013 - Elsevier
Bacteria of the genus Salmonella express nanosyringe-like organelles called type three
secretion systems (T3SSs). These systems promote the secretion of bacterial compounds …

[HTML][HTML] Interaction of Salmonella with host cells through the centisome 63 type III secretion system

JE Galán - Current opinion in microbiology, 1999 - Elsevier
Salmonella enterica engages host cells in a complex two-way biochemical interaction that
results in a variety of responses from both the bacteria and the host cell. Central to this …