Osteoarthritis represents the most frequently diagnosed condition of the musculoskeletal
system and accounts for a high amount of direct and indirect socioeconomic costs …

Over the past two decades, the field of osteoimmunology has emerged in response to a
range of evidence demonstrating the reciprocal relationship between the immune system …

Although osteoarthritis (OA) is the most common musculoskeletal condition that causes
significant health and social problems worldwide, its exact etiology is still unclear. With an …

Osteoarthritis (OA) is a slowly progressive degenerative disease characterized by gradual
loss of articular cartilage. Since the OA lesion is often localized to weight-bearing cartilage …

Bone destruction is a frequent and clinically serious event in patients with rheumatoid
arthritis (RA). Local joint destruction can cause joint instability and often necessitates …

Osteoarthritis is first and foremost the ongoing destruction of the articular cartilages of joints.
Therefore, the extracellular matrix and the cells of the articular cartilages are the primary …

Osteoarthritis (OA) is associated with cartilage degeneration and an accompanying
inflammatory syndrome of the synovium in addition to alteration of the subchondral bone …

Osteoarthritis (OA) induces inflammation and degeneration of all joint components including
cartilage, joint capsule, bone and bone marrow, and ligaments. Particularly intraarticular …

As the cellular component of articular cartilage, chondrocytes are responsible for
maintaining in a low-turnover state the unique composition and organization of the matrix …

Cartilage damage is a key feature of degenerative joint disorders—primarily osteoarthritis
(OA)—and chronic inflammatory joint diseases, such as rheumatoid arthritis (RA) …