Drug delivery systems from nose to brain
A Misra, G Kher - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
The treatment of brain disorders is particularly challenging due to the presence of a variety
of formidable obstacles to deliver drugs selectively and effectively to the brain. Blood-brain …
of formidable obstacles to deliver drugs selectively and effectively to the brain. Blood-brain …
Recent patents review on intranasal administration for CNS drug delivery
A Misra, V Jogani, K Jinturkar… - Recent patents on drug …, 2008 - ingentaconnect.com
The treatment of brain disorders is the greatest challenge because of a variety of formidable
obstacles in effective drug delivery and maintaining therapeutic concentrations in the brain …
obstacles in effective drug delivery and maintaining therapeutic concentrations in the brain …
Nose-to-brain drug delivery: challenges and progress towards brain targeting in the treatment of neurological disorders
Delivery of therapeutics to the central nervous system for treating psychiatric and
neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease, is a …
neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease, is a …
Intranasal drug delivery for brain targeting
TK Vyas, A Shahiwala, S Marathe… - Current drug delivery, 2005 - ingentaconnect.com
Many drugs are not being effectively and efficiently delivered using conventional drug
delivery approach to brain or central nervous system (CNS) due to its complexity. The brain …
delivery approach to brain or central nervous system (CNS) due to its complexity. The brain …
Insights into direct nose to brain delivery: current status and future perspective
Now a day's intranasal (in) drug delivery is emerging as a reliable method to bypass the
blood–brain barrier (BBB) and deliver a wide range of therapeutic agents including both …
blood–brain barrier (BBB) and deliver a wide range of therapeutic agents including both …
Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors
SH Jeong, JH Jang, YB Lee - Journal of pharmaceutical investigation, 2023 - Springer
Background Cranial nerve-related diseases such as brain tumors, Alzheimer's disease, and
epilepsy are serious diseases that continue to threaten human. Brain-related diseases are …
epilepsy are serious diseases that continue to threaten human. Brain-related diseases are …
Formulation and physiological factors influencing CNS delivery upon intranasal administration
The treatment of central nervous system (CNS) disorders is particularly challenging because
of a variety of formidable barriers to effective and persistent delivery of therapeutic …
of a variety of formidable barriers to effective and persistent delivery of therapeutic …
[PDF][PDF] Nose to brain targeted drug delivery bypassing the blood-brain barrier: an overview.
Z Patel, B Patel, S Patel, C Pardeshi - Drug Invention Today, 2012 - academia.edu
Present review highlights the potential of nasal mucosa as an administration route for
targeting the central nervous system (CNS), in particular, the brain. Delivery of drugs to the …
targeting the central nervous system (CNS), in particular, the brain. Delivery of drugs to the …
Drug delivery and targeting to the brain through nasal route: mechanisms, applications and challenges
K Kashyap, R Shukla - Current drug delivery, 2019 - ingentaconnect.com
Blood-brain barrier (BBB) provides restrictions for the transportation of various therapeutic
agents to the brain. Efforts to directly target the brain by olfactory as well as trigeminal nerve …
agents to the brain. Efforts to directly target the brain by olfactory as well as trigeminal nerve …
Intranasal drug delivery: a novel approach
Y Chugh, P Kapoor, AK Kapoor - Indian Journal of Otolaryngology …, 2009 - ncbi.nlm.nih.gov
Intranasal drug delivery occupies the prime place against newer drug delivery systems to
transport drugs to CNS bypassing the blood brain barrier. Recent advances in molecular …
transport drugs to CNS bypassing the blood brain barrier. Recent advances in molecular …