Ontogeny and Regulation of Ovine Placental Prostaglandin E2 Synthase
RL Martin, WL Whittle, AC Holloway… - Biology of …, 2002 - academic.oup.com
Recent evidence suggests that ovine placental output of prostaglandin (PG) E2 rises
through late gestation partly because of a direct effect of cortisol on PGH2 synthase 2 (PGHS …
through late gestation partly because of a direct effect of cortisol on PGH2 synthase 2 (PGHS …
The pattern of glucocorticoid and estrogen receptors may explain differences in steroid dependency of intrauterine prostaglandin production at parturition in sheep
WL Whittle, AC Holloway, S Lye… - Journal of the …, 2006 - journals.sagepub.com
Background: We have recently described two distinct pathways of intrauterine prostaglandin
(PG) synthesis: a cortisol-dependent/estradiol-independent mechanism within trophoblast …
(PG) synthesis: a cortisol-dependent/estradiol-independent mechanism within trophoblast …
Prostaglandin production at the onset of ovine parturition is regulated by both estrogen-independent and estrogen-dependent pathways
WL Whittle, AC Holloway, SJ Lye, W Gibb… - …, 2000 - academic.oup.com
A current hypothesis of ovine parturition proposes that fetal adrenal cortisol induces
placental E2 production, which, in turn, triggers intrauterine PG production. However, recent …
placental E2 production, which, in turn, triggers intrauterine PG production. However, recent …
Increase in 15-hydroxyprostaglandin dehydrogenase activity in the ovine placentome at parturition and effect of oestrogen
SC Riley, R Leask, JV Selkirk… - … of reproduction and …, 2000 - rep.bioscientifica.com
Prostaglandin F2α (PGF2α) and PGE2 produced by the uterine tissues have long been
considered to be important during pregnancy for the regulation of blood flow (Carter, 1998) …
considered to be important during pregnancy for the regulation of blood flow (Carter, 1998) …
Localisation and temporal changes in prostaglandin G/H synthase-1 and-2 content in ovine intrauterine tissues in relation to glucocorticoid-induced and spontaneous …
WJ McLaren, IR Young, GE Rice - Journal of endocrinology, 2000 - joe.bioscientifica.com
Parturition in the ewe is preceded by an increase in the synthesis of prostaglandins (PGs) by
gestational tissues. To establish the uterine source of these PGs, placental cotyledons, fetal …
gestational tissues. To establish the uterine source of these PGs, placental cotyledons, fetal …
Expression of prostaglandin G/H synthase-1 and-2 in ovine amnion and placenta following glucocorticoid-induced labour onset
WJ McLaren, IR Young, MH Wong… - Journal of …, 1996 - joe.bioscientifica.com
Parturition in the sheep is preceded by an increase in the synthesis of prostaglandins by
intrauterine tissues. Prostaglandin G/H synthase (PGHS) is the central enzyme involved in …
intrauterine tissues. Prostaglandin G/H synthase (PGHS) is the central enzyme involved in …
Canine placental prostaglandin E2 synthase: expression, localization, and biological functions in providing substrates for prepartum PGF2alpha synthesis
A Gram, B Fox, U Büchler, A Boos… - Biology of …, 2014 - academic.oup.com
The prepartum output of PGF2alpha in the bitch is associated with increased placental
PGE2-synthase (PTGES) mRNA levels. Contrasting with this is a decreased expression of …
PGE2-synthase (PTGES) mRNA levels. Contrasting with this is a decreased expression of …
Immunohistochemical localization of prostaglandin G/H synthase 1 and 2 in sheep placenta after glucocorticoid-induced and spontaneous labour.
WJ McLaren, IR Young, GE Rice - Journal of reproduction and …, 2000 - europepmc.org
Enhanced prostaglandin production and release by the placenta is an essential element in
the normal transition to labour in many animal species. In sheep, expression of …
the normal transition to labour in many animal species. In sheep, expression of …
Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation
W Gibb, SG Matthews, JRG Challis - Biology of reproduction, 1996 - academic.oup.com
In numerous animal species, increased prostaglandin output by intrauterine tissues occurs
in association with parturition. In the sheep, prostaglandin H synthase (PGHS) is particularly …
in association with parturition. In the sheep, prostaglandin H synthase (PGHS) is particularly …
Temporal and tissue-specific expression of prostaglandin receptors EP2, EP3, EP4, FP, and cyclooxygenases 1 and 2 in uterus and fetal membranes during bovine …
Uteroplacental prostaglandins (PGs) play pivotal roles in maintenance and/or termination of
pregnancy in mammals. Regulation of PG biosynthetic and signaling mechanisms in …
pregnancy in mammals. Regulation of PG biosynthetic and signaling mechanisms in …