Conceptus-derived prostaglandins regulate endometrial function in sheep

P Dorniak, FW Bazer, G Wu… - Biology of …, 2012 - academic.oup.com
In sheep, the trophectoderm of the elongating conceptus secretes interferon tau (IFNT) and
prostaglandins (PGE2, PGF2alpha, PGI2). The PGs are derived from PG synthase 2 …

Expression of enzymes of cyclooxygenase pathway and secretion of prostaglandin E2 and F2α by porcine myometrium during luteolysis and early pregnancy

A Franczak, G Kotwica, B Kurowicka, A Oponowicz… - Theriogenology, 2006 - Elsevier
Past studies of uterine prostaglandin (PGs) and pig reproduction have focused on
endometrial rather than myometrial PGs. This study documents the synthesis and secretion …

Expression of prostaglandin endoperoxide H synthase 1 and 2 in human placenta at term

L Macchia, R Di Paola, MC Guerrese… - Biochemical and …, 1997 - Elsevier
Prostaglandins play an important role in reproduction, particularly in pregnancy and
parturition. We investigated the expression of prostaglandin endoperoxide H synthase …

Expression of microsomal prostaglandin E synthase in bovine endometrium: coexpression with cyclooxygenase type 2 and regulation by interferon-τ

J Parent, P Chapdelaine, J Sirois, MA Fortier - Endocrinology, 2002 - academic.oup.com
Prostaglandins (PGs) are important regulators of reproductive functions. In ruminants,
interferon (IFN)-τ is the embryonic signal responsible for recognition of pregnancy. This is …

Localization and expression of prostaglandin E2 receptors in human placenta and corresponding fetal membranes with labor

PL Grigsby, SR Sooranna, DE Brockman… - American journal of …, 2006 - Elsevier
OBJECTIVE: The effects of prostaglandin E2 (PGE2) are mediated through G-protein
coupled receptors, acting via different second messengers. The aim of this study was to …

Effect of oxytocin and estradiol on uterine prostaglandin release in nonpregnant and early-pregnant ewes

KM Burgess, MM Ralph, G Jenkin… - Biology of …, 1990 - academic.oup.com
The effects of exogenous oxytocin (OT) and estradiol-17β (E2) on plasma concentrations of
prostaglandin (PG) E2 and 13, 14-dihydro-15-keto-PGF2α (PGFM) were investigated on Day …

Advancement of Uterine Secretion of Prostaglandin E2 by Treatment with Progesterone and Transfer of Asynchronous Embryos

DL Vincent, S Meredith, EK Inskeep - Endocrinology, 1986 - academic.oup.com
Abstract Effects of treatment with progesterone early after estrus and the age of the
blastocyst in the uterus on day-6 postestrus on uteroovarian venous concentrations of …

Molecular characterization of bovine prostaglandin G/H synthase-2 and regulation in uterine stromal cells

J Liu, M Antaya, AK Goff, D Boerboom… - Biology of …, 2001 - academic.oup.com
Abstract Prostaglandin G/H synthase (PGHS) is a key rate-limiting enzyme in the
prostaglandin biosynthetic pathway, and prostaglandins play a central role in the control of …

Regulated expression of prostaglandin endoperoxide synthase-2 by uterine stroma

AL Jacobs, D Hwang, J Julian, DD Carson - Endocrinology, 1994 - academic.oup.com
Our previous studies demonstrated that interleukin-1 alpha (IL-1 alpha) and soluble factors
secreted by polarized uterine luminal epithelial cells (UEC) stimulate prostaglandin (PG) …

Ovarian and uterine prostaglandin E2-9-ketoreductase activity in cyclic and pregnant ewes

CJ Beaver, WJ Murdoch - Prostaglandins, 1992 - Elsevier
The regulation of luteal function in sheep appears to be dependent in part upon relative
utero-ovarian concentrations of PGE 2 and PGF 2 α. Prostaglandin E 2-9-ketoreductase …