Expression Profile and Prognostic Values of HOXA Family Members in Laryngeal Squamous Cell Cancer

J Li, M Ye, C Zhou - Frontiers in oncology, 2020 - frontiersin.org
The homeobox A cluster (HOXA) gene family, comprising 11 members, is involved in a wide
spectrum of biological functions in human cancers. However, there is little research on the …

Identification of HOXA1 as a novel biomarker in prognosis of head and neck squamous cell carcinoma

H Li, X Wang, M Zhang, M Wang, J Zhang… - Frontiers in molecular …, 2021 - frontiersin.org
Hox genes, a highly conserved homolog in most animals, play vital functions in cell
development and organ formation. In recent years, researchers have discovered that it can …

Expression of the HOXA gene family and its relationship to prognosis and immune infiltrates in cervical cancer

F Ge, W Tie, J Zhang, Y Zhu… - Journal of clinical …, 2021 - Wiley Online Library
Background The homeobox A cluster (HOXA) gene family is participated in multiple
biological functions in human cancers. To date, little is known about the expression profile …

HOX genes: potential candidates for the progression of laryngeal squamous cell carcinoma

R de Barros e Lima Bueno, A Ramão, DG Pinheiro… - Tumor Biology, 2016 - Springer
Laryngeal squamous cell carcinoma (LSCC) is a very aggressive cancer, considered to be a
subtype of the head and neck squamous cell carcinoma (HNSCC). Despite significant …

HOXB9 expression correlates with histological grade and prognosis in LSCC

C Sun, C Han, P Wang, Y Jin, Y Sun… - BioMed Research …, 2017 - Wiley Online Library
The purpose of this study was to investigate the HOX gene expression profile in laryngeal
squamous cell carcinoma (LSCC) and assess whether some genes are associated with the …

Upregulation of HOX genes promotes cell migration and proliferation in head and neck squamous cell carcinoma

GM Aguiar, A Ramão, JR Plaça, SC Simões… - Tumor …, 2021 - content.iospress.com
BACKGROUND: Expression dysregulation of HOX homeobox genes has been observed in
several cancers, including head and neck squamous cell carcinoma (HNSC). Although …

HOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis

CC Bitu, MFSS Destro, M Carrera, SD da Silva… - BMC cancer, 2012 - Springer
Background HOX genes encode homeodomain-containing transcription factors involved in
the regulation of cellular proliferation and differentiation during embryogenesis. However …

Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma

D Gong, H Zhu, L Zeng, R Hu, J Hu… - … Biology and Medicine, 2021 - journals.sagepub.com
Deregulation of HOX transcription factor family has frequently been observed in multiple
human cancers; however, their role in nasopharyngeal carcinoma remains largely unclear …

Evaluation of the HOXA11 level in patients with lung squamous cancer and insights into potential molecular pathways via bioinformatics analysis

R Zhang, T Zhang, G Zhai, X Guo, Y Qin, T Gan… - World journal of surgical …, 2018 - Springer
Background This study was carried out to discover the underlying role that HOXA11 plays in
lung squamous cancer (LUSC) and uncover the potential corresponding molecular …

HOXA9 expression is associated with advanced tumour stage and prognosis in nasopharyngeal carcinoma

T Liu, C Ji, Y Sun, W Bai - Cancer Management and Research, 2021 - Taylor & Francis
Background Homeobox A9 (HOXA9), a member of the HOX protein family, plays diverse
biological roles in embryonic development and carcinogenesis. The prognostic value of …