The role of HOXA9 in human laryngeal squamous cell carcinoma.

X Sun, B Liu, W Ji, X Ma, X Wang, H Gu - Oncology Research, 2013 - europepmc.org
The present study was performed to investigate the expression of HOXA9 in human
laryngeal squamous cell carcinoma and its possible roles in the progression. The levels of …

HIF-1α or HOTTIP/CTCF promotes head and neck squamous cell carcinoma progression and drug resistance by targeting HOXA9

Q Sun, SY Zhang, JF Zhao, XG Han, HB Wang… - … Therapy-Nucleic Acids, 2020 - cell.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequently diagnosed
cancer worldwide. However, the clinical outcomes remain unsatisfactory. The aim of this …

HOXB7 acts as an oncogenic biomarker in head and neck squamous cell carcinoma

X Wu, J Li, T Yan, X Ke, X Li, Y Zhu, J Yang… - Cancer Cell …, 2021 - Springer
Abstract Background The homeobox gene Homeobox B7 (HOXB7) is overexpressed across
a range of cancers and promotes tumorigenesis through varying effects on proliferation …

HOXA-AS2 may be a potential prognostic biomarker in human cancers: A meta-analysis and bioinformatics analysis

F Zhang, G Zhang, H Zhang, X Pu, F Chi… - Frontiers in …, 2022 - frontiersin.org
Background: Dysregulation of long non-coding (lncRNA) has been reported in various solid
tumors. HOXA cluster antisense RNA 2 (HOXA-AS2) is a newly identified lncRNA with …

HOXA13 promotes cancer cell growth and predicts poor survival of patients with esophageal squamous cell carcinoma

ZD Gu, LY Shen, H Wang, XM Chen, Y Li, T Ning… - Cancer research, 2009 - AACR
Homeobox genes are known to be classic examples of the intimate relationship between
embryogenesis and tumorigenesis. Here, we investigated whether inhibition of HOXA13, a …

Homeobox‐D 1 and FTO form a transcriptional–epigenetic feedback loop to promote head and neck cancer proliferation

C Zhang, L Xie, Z Lin - Cell Biology International, 2023 - Wiley Online Library
Transcription factors (TFs) and N6‐methyladenosine (m6A) modifiers are involved in tumor
progression through transcriptional regulation and posttranscriptional regulation of genes …

HOXB5 acts as an oncogenic driver in head and neck squamous cell carcinoma via EGFR/Akt/Wnt/β-catenin signaling axis

K Lee, JW Chang, C Oh, L Liu, SN Jung… - European Journal of …, 2020 - Elsevier
Introduction Identification of therapeutic targets in head and neck squamous cell carcinoma
(HNSCC) is essential because most of the patients with advanced HNSCC have a poor …

HOXA1 is a radioresistance marker in multiple cancer types

L He, M Liang, W Guo, J Liu, Y Yu - Frontiers in Oncology, 2022 - frontiersin.org
Radiotherapy is an important therapeutic method for patients with cancer. However,
radioresistance can cause treatment failure. Thus, there is an urgent need to investigate …

[HTML][HTML] Upregulation of homeobox gene is correlated with poor survival outcomes in cervical cancer

KJ Eoh, HJ Kim, JY Lee, EJ Nam, S Kim, SW Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
HOX family members encode transcription factors crucial for embryogenesis and may be
associated with carcinogenesis. Here, we evaluated the expression of 39 HOX genes in …

[HTML][HTML] Forced expression of HOXA13 confers oncogenic hallmarks to esophageal keratinocytes

K Nesteruk, VT Janmaat, H Liu, TLM Ten Hagen… - … et Biophysica Acta (BBA …, 2020 - Elsevier
HOXA13 overexpression has been detected in human ESCC tissue and high HOXA13
protein expression is correlated with a shorter median survival time in ESCC patients …