Homeobox genes, a superfamily of evolutionarily conserved developmental genes, function
as critical master regulatory factors in controlling body plan specification and cell fate …

Background Recent studies showed that HOXA1 can promote or suppress the transcription
of target genes via binding to their promoter region, therefore regulating the development …

Transcription factors encoded by Homeobox (HOX) genes play numerous key functions
during early embryonic development and differentiation. Multiple reports have shown that …

Recent decades have witnessed the publication of numerous studies reporting alterations in
the genome and transcriptome of head and neck squamous cell carcinoma (HNSCC) …

Background HOXA cluster antisense RNA 2 (lncRNA HOXA-AS2) is a long noncoding RNA
(lncRNA) that aberrantly expressed in various cancers and is closely associated with cancer …

HOX transcription factors are evolutionarily conserved in many different species and are
involved in important cellular processes such as morphogenesis, differentiation, and …

Objective: This study was to determine the role of HOXB7 in predicting outcomes of patients
with oesophageal squamous cell cancer (OSCC). Methods: Samples were collected from …

Breast cancer (BC) is the most commonly diagnosed cancer and the second leading cause
of cancer‑associated mortality among females worldwide. As a member of the homeobox …

Abstract Background Homeobox A (HOXA) family is involved in the development of
malignancies as either tumor suppressors or oncogenes. However, their roles in …

A growing body of evidence has confirmed the involvement of dysregulated expression of
HOX genes in cancer. HOX genes are a family of 39 transcription factors, divided in 4 …