Comprehensive analysis of mRNA expression profiles in head and neck cancer by using robust rank aggregation and weighted gene coexpression network analysis

Z Cao, Y Ao, Y Guo, S Zhou - BioMed Research International, 2020 - Wiley Online Library
Background. Head and neck squamous cell cancer (HNSCC) is the sixth most common
cancer in the world; its pathogenic mechanism remains to be further clarified. Methods …

HOXC6 promotes migration, invasion and proliferation of esophageal squamous cell carcinoma cells via modulating expression of genes involved in malignant …

L Tang, Y Cao, X Song, X Wang, Y Li, M Yu, M Li, X Liu… - PeerJ, 2019 - peerj.com
Background HOXC6 is a member of the HOX gene family. The elevated expression of this
gene occurs in prostate and breast cancers. However, the role of HOXC6 in esophageal …

Prognostic biomarkers and therapeutic targets in oral squamous cell carcinoma: a study based on cross-database analysis

W Yang, W Zhou, X Zhao, X Wang, L Duan, Y Li, L Niu… - Hereditas, 2021 - Springer
Background Oral squamous cell carcinoma (OSCC) is a malignant cancer, the survival rate
of patients is disappointing. Therefore, it is necessary to identify the driven-genes and …

HOXA13 promotes the proliferation, migration, and invasion of nasopharyngeal carcinoma HNE1 cells by upregulating the expression of Snail and MMP-2

J Liu, H Feng, D Wang, Y Wang, J Luo, S Xu, F Zhao… - Scientific Reports, 2023 - nature.com
Abstract Homeobox A13 (HOXA13) has been verified as an oncogen in some malignancies.
However, its role in nasopharyngeal carcinoma (NPC) is still unclear. This study aims to …

Exploration of target genes of HOXA13 in esophageal squamous cell carcinoma cell line

LY Shen, KN Chen - Cancer letters, 2011 - Elsevier
Homeobox genes encode transcriptional factors which regulate cell proliferation and
differentiation and have been found to be deregulated in many tumors. Previously, we found …

Bioinformatics analysis of the expression of HOXC13 and its role in the prognosis of breast cancer

C Li, J Cui, L Zou, L Zhu, W Wei - Oncology letters, 2020 - spandidos-publications.com
The homeobox (HOX) genes, a class of transcription factors, are known to promote
embryonic development and induce tumor formation. To date, the HOXA and HOXB gene …

The integrated comprehension of lncRNA HOXA-AS3 implication on human diseases

Q Yao, C Wang, Y Wang, X Zhang, H Jiang… - Clinical and Translational …, 2022 - Springer
Long non-coding RNA (lncRNA) is a non-protein-coding RNA with a length of more than 200
nucleotides. Studies have shown that lncRNAs have vital impacts on various pathological …

Silencing lncRNA HOXA10-AS decreases cell proliferation of oral cancer and HOXA10-antisense RNA can serve as a novel prognostic predictor

X Yan, B Cong, Q Chen, L Liu, X Luan… - Journal of …, 2020 - journals.sagepub.com
Objective Long noncoding (lnc) RNAs regulate multiple biological processes including
cancer. Oral squamous cell carcinoma (OSCC) is a common malignancy with poor …

Deregulated HOXB7 expression predicts poor prognosis of patients with esophageal squamous cell carcinoma and regulates cancer cell proliferation in vitro and in …

H Li, LY Shen, WP Yan, B Dong, XZ Kang, L Dai… - PLoS …, 2015 - journals.plos.org
Background We observed abnormal HOXB7 expression in esophageal squamous cell
carcinoma (ESCC) previously. This study was to evaluate the prognostic significance of …

[HTML][HTML] Next-generation sequencing identifies HOXA6 as a novel oncogenic gene in low grade glioma

J Xiulin, C Wang, J Guo, C Wang, C Pan… - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Background: Low grade glioma is one of the most common lethal cancers in the human
nervous system. Emerging evidence has demonstrated that homeobox A cluster (HOXA) …