Diet-induced obesity contributes to the development of type 2 diabetes, insulin resistance,
metabolic inflammation, oxidative and endoplasmic reticulum (ER) stress. Overall, obesity is …

The gut microbiome plays an important role in obesity and Type 2 diabetes (T2D); however,
it remains unclear whether the gut microbiome could clarify the dietary versus genetic origin …

Background It is well known that the microbiota of high-fat (HF) diet-induced obese mice
differs from that of lean mice, but to what extent, this difference reflects the obese state or the …

Gut microbiota play important roles in host metabolism, especially in diabetes. However,
why different diets lead to similar diabetic states despite being associated with different …

Introduction With improvements in living conditions, modern individuals exhibit a
pronounced inclination towards a high-fat diet, largely because of its distinctive gustatory …

Background Although obesity is caused by different factors, individual susceptibility to
obesity differs among people under the same circumstances. The microbiota in the caecum …

Dietary interventions with probiotics have been widely reported to be effective in regulating
obesity, and the intestinal microbiota is considered to be an important environmental factor …

Calorie restriction (CR) extends lifespan and elicits numerous effects beneficial to health
and metabolism in various model organisms, but the underlying mechanisms are not …

The major characteristics of obesity are abnormal lipid metabolism, chronic inflammation,
and imbalanced gut microbiota. It has been reported that lactic acid bacteria (LAB) possess …

Methods: Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18
weeks. Metabolic parameters and gut microbiota changes were then characterized. Results …