Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …

Combining diagnosis with therapy, magnetic iron oxide nanoparticles (INOPs) act as an
important vehicle for drug delivery. However, poor biocompatibility of INOPs limits their …

Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range
of applications. During recent years, one of the most challenging goals is the development of …

Introduction In the field of drug delivery, controlling the release of therapeutic substances at
localized targets has become a primary focus of medical research, especially in the field of …

The field of nanomedicine has recently emerged as a product of the expansion of a range of
nanotechnologies into biomedical science, pharmacology and clinical practice. Due to the …

Highlights•CNS diseases affect millions of people globally and cause economic
burden.•Development of an effective delivery system to the brain is urgently required for …

Gliomas are the most common primary brain tumors and have a very dismal prognosis.
However, recent advancements in nanomedicine and nanotechnology provide opportunities …

Magnetic iron oxide nanoparticles (MIONs) are among the first generation of nanomaterials
that have advanced to clinic use. A broad range of biomedical techniques have been …

OBJECTIVE: Superparamagnetic iron oxide nanoparticle magnetic resonance imaging
(MRI) contrast agents are gaining use in the central nervous system. The purpose of this …