The aim of this study was to evaluate the most common ABCB1 (MDR1, P-glycoprotein)
polymorphisms in the population of R. Macedonia and compare the allele and haplotype …

Abstract The ABCB1/MDR-1 gene, which encodes P-glycoprotein, is highly polymorphic. We
analyzed 278 healthy Brazilian individuals through PCR–RFLP to identify ABCB1 variants …

Abstract Objective The ABCB1 (MDR1) multidrug transporter plays a key role in determining
drug bioavailability. Differences in drug response exist among different ethnic groups …

The three functional single-nucleotide polymorphisms (SNPs) of the MDR1 gene, C1236T,
G2677T/A, and C3435T, exhibit an interpopulation difference. In this study, we analyzed the …

The genetic variability, haplotype profile and ethnic differences of MDR1 polymorphisms in
healthy Roma and Hungarian populations were analyzed and the results were compared …

The multidrug resistance gene (MDR1 or ABCB1) codes for P-glycoprotein, which plays an
important role in regulating absorption, distribution, and elimination of drugs. We examined …

Single nucleotide polymorphisms (SNPs) in the MDR1 gene that are responsible for drug
efflux can cause toxicity. Therefore, this study determined the SNPs of the Korean MDR1 …

The multidrug resistance gene (MDR1) plays an important role in the transport of a wide
range of drugs and elimination of xenobiotics from the body. Identification of polymorphisms …

Aims The aim of the study was to determine whether a correlation exists between MDR1
(ABCB1) gene polymorphisms at positions 3435 (C3435T) and 2677 (G2677T (A)) and the …

Objectives There is increasing evidence that polymorphism of the ABCB1 (MDR1) gene
contributes to interindividual variability in bioavailability and tissue distribution of P …