BACKGROUND The mechanisms involved in the initiation and maintenance of Crohn's
disease are poorly understood. Previous studies have demonstrated an increased number …

Abstract Interleukin 33 (IL-33) is a cytokine preferentially elevated in acute ulcerative colitis
(UC), inferring a role in its pathogenesis. The role of IL-33 in intestinal inflammation is …

To investigate the relationship between serum concentrations of interleukin‐8 (IL‐8) and
disease activity in inflammatory bowel disease, serum IL‐8 concentrations were measured …

Abstract Dysregulation of interleukin-8 (IL-8) production has been proposed to contribute to
intestinal inflammation in inflammatory bowel disease (IBD) patients. Previous studies …

Objective. The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative
colitis (UC) are chronic inflammatory conditions that affect the gastrointestinal tract. In …

Interleukin-6 (IL-6) is a key mediator cytokine of the immune response as well as a regulator
of many physiological and pathological processes. In Crohn's disease (CD), cytokine …

Background and aim: Interleukin (IL) 17 is a cytokine which exerts strong proinflammatory
activities. In this study we evaluated changes in IL-17 expression in the inflamed mucosa …

Background & Aims There is evidence that immune dysfunction precedes symptoms of
inflammatory bowel disease (IBD) by several years. Characterization of preclinical systemic …

AIM: The aim of this study was to evaluate the association between ulcerative colitis activity
and plasma or mucosal concentrations of interleukin (IL)-18. METHODS: Il-18 …

Background: Mucosal IL-13 Receptor alpha 2 (IL13RA2) mRNA expression is one of the
best predictive markers for primary non-responsiveness to infliximab therapy in patients with …