The most common theories about the pathogenesis of idiopathic kidney stones consider
precipitation of calcium phosphate (CaP) within the kidneys critical for the development of …

Increased dietary oxalate does not increase urinary calcium oxalate saturation in
hypercalciuric rats. Background Human calcium oxalate (CaOx) nephrolithiasis may occur if …

Using ethylene glycol (EG) and vitamin D3 as crystal-inducing diet (CID) in rats, we
investigated the effect of the dosage of EG on the generation of chronic calcium oxalate …

Single intraperitoneal injections of three, seven, or 10 mg. of sodium oxalate per 100 gm. of
rat body weight were administered to male Sprague-Dawley rats. At various times after the …

Background/Aims: Hyperoxaluria is a major risk factor for recurrent urolithiasis and
nephrocalcinosis. We tested an oral therapy with a crystalline, cross-linked formulation of …

The establishment of an experimental animal model would be useful to study the
mechanism of kidney stone formation. A calcium kidney stone model in rats induced by …

Our own studies and those of others have shown that the incidence of calcium oxalate
stones and plaques is markedly increased by nephrotoxins. The possible role of oxalate as …

Calcium oxalate crystal localization and osteopontin immunostaining in genetic
hypercalciuric stone-forming rats. Background The inbred genetic hypercalciuric stone …

Oxalate or calcium oxalate crystal-induced tissue damage could be conducive to renal stone
disease. We studied the response of renal proximal (LLC-PK1 and MDCK-II) and collecting …

We employed an experimental hyperoxaluric protocol involving the administration of 1 per
cent ethylene glycol drinking water to rats to determine (i) the location and mechanism of …