In the present study, we exposed rats to a crystal-inducing diet (CID) consisting of vitamin D3
and 0.5% ethylene glycol (EG), and we investigated histologically the kidney damage …

The formation of calcium oxalate crystals was induced in rat kidneys by intraperitoneal
injections of sodium oxalate. After varying lengths of time of sodium oxalate challenge the rat …

Calcium oxalate monohydrate crystals stimulate gene expression in renal epithelial cells.
Primary or secondary hyperoxaluria is associated with calcium oxalate nephrolithiasis …

Deposition of calcium oxalate is responsible for the pathologic manifestations of oxalosis
and may contribute to multiorgan dysfunction in uremia and to the progression of renal …

Oxalate is toxic to renal tubular cells only at supraphysiologic concentrations. Background
Oxalate-induced tissue damage may play an initiating role in the pathophysiology of calcium …

In kidneys of healthy rats submitted to a crystal-inducing diet (CID) with ethylene glycol (EG)
and NH 4 Cl, the fate of retained crystals in the papillar region is studied during a recovery …

Abstract Background/Aims: Hypercalciuria is the most common identifiable risk factor
predisposing to CaOx stone formation. Increased oral magnesium intake may lead to …

Purpose: Unraveling the mechanisms leading to clinically active calcium oxalate (CaOx)
stone disease and the development of effective medical therapies to treat it have been …

Interstitial calcium oxalate (CaOx) crystals can be found in primary oxalosis and in
secondary hyperoxaluria. In a rat model for nephrolithiasis, we investigated whether such …

The early phases of calcium oxalate crystal formation in rat kidneys after intraperitoneal
challenge with sodium oxalate were examined. From the results we conclude that the …