Mechanism of calcium oxalate renal stone formation and renal tubular cell injury

M Tsujihata - International Journal of Urology, 2008 - Wiley Online Library
Formation of calcium oxalate stones tends to increase with age and begins from the
attachment of a crystal formed in the cavity of renal tubules to the surface of renal tubular …

Effect of vitamin A supplemented diet on calcium oxalate renal stone formation in rats

M Bardaoui, R Sakly, F Neffati, MF Najjar… - Experimental and …, 2010 - Elsevier
OBJECTIVES: To study the effect of a vitamin A supplemented diet on calcium-oxalate stone
formation in rats and to test its expected action in the dissolution of renal calculi. MATERIAL …

Stone formation in genetic hypercalciuric rats

DA Bushinsky, MD Grynpas, EL Nilsson, Y Nakagawa… - Kidney international, 1995 - Elsevier
Stone formation in genetic hypercalciuric rats. Our genetic hypercalciuric (GH) rats have
been selected and inbred for 29 generations to maximize urine calcium (U Ca) excretion …

Intracellular events in the initiation of calcium oxalate stones

JA Jonassen, LC Cao, T Honeyman… - Nephron Experimental …, 2004 - karger.com
This review summarizes our current understanding of intracellular events in the initiation of
kidney stone formation, focusing on results from studies using renal epithelial cells in vitro …

Effects of Oxalate 0n HK-2 Cells, a Line of Proximal Tubular Epithelial Cells From Normal Human Kidney

A Bhandari, S Koul, A Sekhon, SK Pramanik… - The Journal of …, 2002 - auajournals.org
Purpose: Oxalate, a metabolic end product, is a major constituent of majority of renal stones.
Previous studies with LLC-PK1 cells, a line of proximal renal epithelial cells of porcine …

[HTML][HTML] Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis

YH Chen, HP Liu, HY Chen, FJ Tsai, CH Chang… - Kidney international, 2011 - Elsevier
Several animal species are used to study calcium oxalate urolithiasis; however, an ideal
model has yet to be identified. We used Drosophila as a model organism and fed the flies …

Dietary oxalate and kidney stone formation

T Mitchell, P Kumar, T Reddy… - American Journal …, 2019 - journals.physiology.org
Dietary oxalate is plant-derived and may be a component of vegetables, nuts, fruits, and
grains. In normal individuals, approximately half of urinary oxalate is derived from the diet …

Etiology of calcium oxalate nephrolithiasis in rats. I. Can this be a model for human stone formation?

WC De Bruijn, ER Boeve, P Van Run… - Scanning …, 1995 - digitalcommons.usu.edu
Crystal retention is studied in a rat-model system as a possible mechanism for the etiology of
human nephrolithiasis. A crystal-inducing diet (CID) of ethylene glycol plus NH 4 Cl in their …

Genetic hypercalciuric stone-forming rats

DA Bushinsky, KK Frick, K Nehrke - Current opinion in nephrology …, 2006 - journals.lww.com
Genetic hypercalciuric stone-forming rats : Current Opinion in Nephrology and Hypertension
Genetic hypercalciuric stone-forming rats : Current Opinion in Nephrology and Hypertension …

[HTML][HTML] Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: inflammatory changes are mainly associated with crystal deposition

S Joshi, W Wang, SR Khan - PLoS One, 2017 - journals.plos.org
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes
renal injury and inflammation leading to number of diseases including chronic kidney …