Characterization of common and rare mutations in EGFR and associated clinicopathological features in a large population of Chinese patients with lung cancer
B Wei, P Ren, C Zhang, Z Wang, B Dong… - … -Research and Practice, 2017 - Elsevier
Lung cancer with EGFR mutation is often associated pathological characteristics and good
responses to EGFR tyrosine kinase inhibitors (TKIs). However, certain types of rare EGFR …
responses to EGFR tyrosine kinase inhibitors (TKIs). However, certain types of rare EGFR …
Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study
X Lin, M Peng, Q Chen, M Yuan, R Chen… - Frontiers in …, 2021 - frontiersin.org
Background Epidemiological surveys have suggested that lung cancer has inherited
susceptibility and shows familial aggregation. However, the distribution and prevalence of …
susceptibility and shows familial aggregation. However, the distribution and prevalence of …
[HTML][HTML] Uncommon EGFR mutations in lung adenocarcinoma: features and response to tyrosine kinase inhibitors
A Brindel, W Althakfi, M Barritault, E Watkin… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
Background EGFR mutant non-small cell lung cancer (NSCLC) is a heterogeneous disease.
The treatment for frequent EGFR mutations relies on tyrosine kinase inhibitors (TKIs); the …
The treatment for frequent EGFR mutations relies on tyrosine kinase inhibitors (TKIs); the …
EGFR mutations in non-small cell lung cancer: an audit from West China Hospital
Y Tang, W Wang, K Zheng, L Jiang, Y Zou… - Expert Review of …, 2016 - Taylor & Francis
Objectives: To discover the incidence and characteristics of EGFR mutations in non-small
cell lung cancer (NSCLC) in a single, large cohort as a part of routine diagnostic …
cell lung cancer (NSCLC) in a single, large cohort as a part of routine diagnostic …
[HTML][HTML] Uncommon EGFR mutations in lung adenocarcinomas: Clinical features and response to tyrosine kinase inhibitors
A Brindel, W Althakfi, M Barritault… - Annals of …, 2018 - annalsofoncology.org
Background: The detection of pro-oncogenic mutations such as mutations in the epidermal
growth factor receptor (EGFR) allowed the development of targeted therapies as inhibitor of …
growth factor receptor (EGFR) allowed the development of targeted therapies as inhibitor of …
A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer
HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
Introduction Patients with non-small cell lung cancer (NSCLC) harboring uncommon
epidermal growth factor receptor (EGFR) mutations are a heterogeneous group exhibiting …
epidermal growth factor receptor (EGFR) mutations are a heterogeneous group exhibiting …
EGFR Mutations in Surgically Resected Fresh Specimens from 697 Consecutive Chinese Patients with Non-Small Cell Lung Cancer and Their Relationships with …
Y Lai, Z Zhang, J Li, D Sun, Y Zhou, T Jiang… - International journal of …, 2013 - mdpi.com
We aimed to reveal the true status of epidermal growth factor receptor (EGFR) mutations in
Chinese patients with non-small cell lung cancer (NSCLC) after lung resections. EGFR …
Chinese patients with non-small cell lung cancer (NSCLC) after lung resections. EGFR …
Next‐generation sequencing of Chinese stage IV lung cancer patients reveals an association between EGFR mutation status and survival outcome
F Li, X Du, H Zhang, T Ju, C Chen, Q Qu… - Clinical …, 2017 - Wiley Online Library
Large‐scale genomic characterization of non‐small cell lung cancer (NSCLC) has revealed
several putative oncogenic driver mutations that may constitute druggable therapeutic …
several putative oncogenic driver mutations that may constitute druggable therapeutic …
[HTML][HTML] Distinct epidemiology and clinical consequence of classic versus rare EGFR mutations in lung adenocarcinoma
Z Lohinai, MA Hoda, K Fabian, G Ostoros… - Journal of thoracic …, 2015 - Elsevier
Introduction Although classic sensitizing mutations of epidermal growth factor receptor
(EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung …
(EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung …
Analysis of EGFR mutation and clinical features of lung cancer in Yunnan
YC Zhou, YP Lin, Q Li, LY Ma, X Liu… - Zhonghua zhong liu …, 2020 - europepmc.org
Objective: To analyze the EGFR mutation profile of lung cancer patients in Yunnan, and to
provide evidence for clinical personalized treatment. Methods: Demographic and clinical …
provide evidence for clinical personalized treatment. Methods: Demographic and clinical …
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