Background Oligoclonal bands (OCBs) unique to the cerebrospinal fluid are used in the
diagnosis of multiple sclerosis (MS). The precise prevalence of OCBs in MS and clinically …

BACKGROUND: Multiple Sclerosis (MS) patients lacking CSF oligoclonal bands are
purported to have a milder course of disease. We reviewed the natural history of oligoclonal …

Two or more oligoclonal IgG bands (OB) detected by separation of cerebrospinal fluid (CSF)
proteins while not demonstrable in corresponding serum reflect a local B-cell response …

Objective: Oligoclonal band (OCB) negative multiple sclerosis (MS) is well recognised but
uncommon, studied in only a few usually small case series. These reached differing …

Background: With the advent of MRI scanning, the value of lumbar puncture to assess
oligoclonal band (OCB) statusfor the diagnosis of multiple sclerosis (MS) is increasingly …

The diagnosis of multiple sclerosis is based on dissemination in time and space. Before
2010 lack of evidence for dissemination in space could be substituted by a paraclinical test …

Oligoclonal immunoglobulin G (IgG) bands (OCBs) are a useful diagnostic tool to detect a
central humoral response. In particular, cerebrospinal fluid (CSF)-restricted OCBs represent …

Abstract Background Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid
(CSF) are a frequent phenomenon in multiple sclerosis (MS) patients, their relationship with …

The presence of oligoclonal bands in clinically isolated syndromes is an independent risk
factor for developing multiple sclerosis and has been largely excluded from the more recent …

We reviewed the records of 391 patients who had presented with a Clinically Isolated
Syndrome and selected 205 who had performed a baseline spinal tap and MRI scan. We …