Cancer-associated cachexia is a complex metabolic condition characterized by the
progressive loss of body fat and deterioration of muscle mass. Although the cellular and …

Background Cancer cachexia is largely irreversible, at least via nutritional means, and
responsible for 20–40% of cancer‐related deaths. Therefore, preventive measures are of …

Cancer cachexia (CC) accounts for 20%–40% of cancer-related deaths. Mitochondrial
aberrations have been shown to precede muscle atrophy in different atrophy models …

Background More than 650 million people are obese (BMI> 30) worldwide, which increases
their risk for several metabolic diseases and cancer. While cachexia and obesity are at …

Cancer cachexia (CC) results in impaired muscle function and quality of life and is the
primary cause of death for∼ 20%–30% of patients with cancer. We demonstrated …

Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle
mass due to imbalance between protein synthesis and degradation, which is related with …

Background Muscle protein turnover regulation during cancer cachexia is being rapidly
defined, and skeletal muscle mitochondria function appears coupled to processes regulating …

Cancer cachexia is a frequently neglected debilitating syndrome that, beyond representing a
primary cause of death and cancer therapy failure, negatively impacts on patients' quality of …

New Findings• What is the central question of this study? We explored whether experimental
cancer‐induced cachexia may alter mitochondrial respiratory chain (MRC) complexes and …

Cancer-induced cachexia has a negative impact on quality of life and adversely affects
therapeutic outcomes and survival rates. It is characterized by, often severe, loss of muscle …