Cell death mechanisms have been associated with the development of inflammatory bowel
diseases in humans and mice. Recent studies suggested that a complex crosstalk between …

Background—Tumour necrosis factor (TNF) α and TNF-β are soluble ligands binding to TNF
receptors with similar activities; soluble TNF receptors neutralise TNF activity by acting as …

Inflammation and cancer have been viewed as closely linked for many years. This link is not
merely a loose association but causative. In colorectal cancer (CRC), chronic inflammation …

Neutralizing tumour necrosis factor (TNF) antibodies have been widely used to treat
inflammatory bowel disease (IBD) in the clinical practice. In this review, the principal …

Introduction Inflammation is a very important part of innate immunity and is regulated in
many steps. One such regulating step is the cytokine network, where tumor necrosis factor α …

Background: Background: Tumor necrosis factor-α (TNF-α), may be involved in the
pathogenesis of inflammatory bowel diseases (IBDs). The aim of this study was to evaluate …

Inflammatory conditions are characterized by activation of the transcription factor nuclear
factor kappa B (NF-κB), resulting in the expression of NF-κB-regulated, inflammation-related …

Altered mucosal integrity and increased cytokine production, including tumor necrosis factor
(TNF), are the hallmarks of inflammatory bowel disease (IBD). In this study, we addressed …

Inflammatory bowel disease is known as the most chronic inflammatory disorder in colon,
which subsequently progresses to intestinal obstruction and fistula formation. Many studies …

The biological impact of the NF-κB transcriptional system in various intestinal biological
processes such as cellular proliferation, differentiation and survival, inflammation, and …