The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system
that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a …

Alveolar hypoxia, a consequence of many lung diseases, can have adverse effects on the
pulmonary vasculature. The changes that occur in the pulmonary circulation with exposure …

Pulmonary arterial hypertension (PAH) is a severe and progressive disease that usually
culminates in right heart failure and death if left untreated. Although there have been …

The pulmonary circulation is a low resistance and low pressure system. Sustained
pulmonary vasoconstriction and excessive vascular remodeling often occur under …

Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

Many chronic lung diseases are associated with prolonged exposure to alveolar hypoxia,
resulting in the development of pulmonary hypertension. While the exact mechanisms …

Pulmonary hypertension is a fatal disease of multiple etiologies that is estimated to affect
over 100 million people worldwide. The disease is defined hemodynamically as a mean …

Pulmonary vasoconstriction is believed to be an early component of pulmonary arterial
hypertension. Intracellular calcium concentration ([Ca2+] i) is a major trigger for pulmonary …

Pulmonary arterial hypertension (PAH) is a hemodynamic abnormality that ultimately results
in mortality due to right heart failure. Although the clinical manifestations of primary and …

Pulmonary circulation is an important circulatory system in which the body brings in oxygen.
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease that predominantly …