Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes
RS Sankhala, V Dussupt, G Donofrio, GD Gromowski… - Cell reports, 2023 - cell.com
Zika virus (ZIKV) is an emerging pathogen that causes devastating congenital defects. The
overlapping epidemiology and immunologic cross-reactivity between ZIKV and dengue virus …
overlapping epidemiology and immunologic cross-reactivity between ZIKV and dengue virus …
Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III
Y Wu, S Li, L Du, C Wang, P Zou, B Hong… - Emerging microbes & …, 2017 - Taylor & Francis
The Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, has emerged as a
global public health concern. Pre-existing cross-reactive antibodies against other …
global public health concern. Pre-existing cross-reactive antibodies against other …
Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
The 2015–2016 outbreak of Zika virus (ZIKV) disease has affected many countries and is a
major public health concern. ZIKV is associated with fetal microcephaly and neurological …
major public health concern. ZIKV is associated with fetal microcephaly and neurological …
Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype
KA Dowd, CR DeMaso, RS Pelc, SD Speer, ARY Smith… - Cell reports, 2016 - cell.com
Recent epidemics of Zika virus (ZIKV) have been associated with congenital malformation
during pregnancy and Guillain-Barré syndrome. There are two ZIKV lineages (African and …
during pregnancy and Guillain-Barré syndrome. There are two ZIKV lineages (African and …
[HTML][HTML] Human antibody response to Zika targets type-specific quaternary structure epitopes
MH Collins, HA Tu, C Gimblet-Ochieng, GJA Liou… - JCI insight, 2019 - ncbi.nlm.nih.gov
The recent Zika virus (ZIKV) epidemic in the Americas has revealed rare but serious
manifestations of infection. ZIKV has emerged in regions endemic for dengue virus (DENV) …
manifestations of infection. ZIKV has emerged in regions endemic for dengue virus (DENV) …
A new class of broadly neutralizing antibodies that target the glycan loop of Zika virus envelope protein
Zika virus (ZIKV) infection poses a serious threat to human health. However, no licensed
vaccine or therapeutic drug is currently available for ZIKV. We have previously shown that …
vaccine or therapeutic drug is currently available for ZIKV. We have previously shown that …
Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor
V Dussupt, RS Sankhala, GD Gromowski, G Donofrio… - Nature medicine, 2020 - nature.com
Zika virus (ZIKV) has caused significant disease, with widespread cases of neurological
pathology and congenital neurologic defects. Rapid vaccine development has led to a …
pathology and congenital neurologic defects. Rapid vaccine development has led to a …
Development of a potent and protective germline-like antibody lineage against Zika virus in a convalescent human
Zika virus (ZIKV) specific neutralizing antibodies hold great promise for antibody-based
interventions and vaccine design against ZIKV infection. However, their development in …
interventions and vaccine design against ZIKV infection. However, their development in …
Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality
S Maciejewski, TJ Ruckwardt, KM Morabito… - Science translational …, 2020 - science.org
The emergence of Zika virus (ZIKV) in the Americas stimulated the development of multiple
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …
[HTML][HTML] Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico
DF Robbiani, L Bozzacco, JR Keeffe, R Khouri… - Cell, 2017 - cell.com
Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …