Towards second generation hypericin based photosensitizers for photodynamic therapy
Its outstanding ability to generate singlet oxygen or reactive oxygen species upon irradiation
with light makes hypericin one of the most powerful photosensitizers to be found in nature …
with light makes hypericin one of the most powerful photosensitizers to be found in nature …
Progress in the chemistry of second generation hypericin based photosensitizers
Its outstanding ability to generate singlet oxygen or reactive oxygen species upon irradiation
with light makes hypericin one of the most powerful photosensitizers to be found in Nature …
with light makes hypericin one of the most powerful photosensitizers to be found in Nature …
In vitro study of the photocytotoxicity of bathochromically-shifted hypericin derivatives
Hypericin has excellent photosensitizing properties and displays favorable tumouritropic
characteristics, but at the same time exhibits minimal dark toxicity. As such, the compound is …
characteristics, but at the same time exhibits minimal dark toxicity. As such, the compound is …
A route to amino functionalized hypericin derivatives and their chemical and photochemical properties pertaining to photodynamic therapy
B Lackner, K Bretterbauer, C Schwarzinger… - Monatshefte für Chemie …, 2005 - Springer
Syntheses of amino functionalized hypericin derivatives could be achieved starting from the
recently prepared emodin derived 1, 3, 8-trimethoxy-6-amino-9, 10-anthraquinone. Our …
recently prepared emodin derived 1, 3, 8-trimethoxy-6-amino-9, 10-anthraquinone. Our …
Hypericin-a new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules
P Miskovsky - Current drug targets, 2002 - ingentaconnect.com
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus
Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent …
Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent …
Hypericin in photobiological assays: An overview
GP de Andrade, TFM de Souza, G Cerchiaro… - Photodiagnosis and …, 2021 - Elsevier
Hypericin is considered a potent photosensitizer for use in antitumor and antimicrobial
photodynamic therapy (PDT). This review presents the primary biological results obtained …
photodynamic therapy (PDT). This review presents the primary biological results obtained …
Cellular mechanisms and prospective applications of hypericin in photodynamic therapy
T Kiesslich, B Krammer… - Current medicinal …, 2006 - ingentaconnect.com
During the last decades, Photodynamic Therapy (PDT) has been established as a powerful
alternative approved by health agencies of several countries for treatment of various …
alternative approved by health agencies of several countries for treatment of various …
Synthesis and Properties of 10, 11-Dibenz-imidazolyl-10, 11-didesmethyl-hypericin–The First Heterocyclically Substituted Hypericin Derivative
B Lackner, C Etzlstorfer, H Falk - Monatshefte für Chemie/Chemical …, 2004 - Springer
The synthesis of the first heterocyclically substituted title hypericin derivative was achieved
starting from 6-benzimidazolyl-tri-O-methyl-6-desmethylemodin. The chemical as well as …
starting from 6-benzimidazolyl-tri-O-methyl-6-desmethylemodin. The chemical as well as …
Hypericin-mediated photodynamic therapy for the treatment of cancer: a review
X Dong, Y Zeng, Z Zhang, J Fu, L You… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Hypericin is a polycyclic aromatic naphthodianthrone that occurs naturally. It is
also an active ingredient in some species of the genus Hypericum. Emerging evidence …
also an active ingredient in some species of the genus Hypericum. Emerging evidence …
Hypericin in cancer treatment: more light on the way
P Agostinis, A Vantieghem, W Merlevede… - The international journal …, 2002 - Elsevier
Photodynamic therapy (PDT) has been described as a promising new modality for the
treatment of cancer. PDT involves the combination of a photosensitizing agent …
treatment of cancer. PDT involves the combination of a photosensitizing agent …
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