High-fat diet accelerate hepatic fatty acids synthesis in offspring male rats induced by perinatal exposure to nonylphenol

H Zhang, C Song, R Yan, H Cai, Y Zhou… - BMC Pharmacology and …, 2021 - Springer
Background Low dose of NP exposure can alter adipose tissue formation, and the intake of
high-fat diet (HFD) can also lead to the fatty liver disease. We investigated the combined …

High‐Fat Diet Promotes Adipogenesis in Offspring Female Rats Induced by Perinatal Exposure to 4‐Nonylphenol

H Zhang, W Ke, X Chen, Y Han, Y Xiong… - BioMed Research …, 2023 - Wiley Online Library
Background. Both high‐fat diet (HFD) and 4‐nonylphenol (4‐NP) could affect fat formation in
adipose tissue individually. We investigated whether HFD promote abnormal adipose tissue …

Perinatal exposure to 4-nonylphenol can affect fatty acid synthesis in the livers of F1 and F2 generation rats

H Zhang, W Xue, Y Zhu, W Huo, B Xu… - Toxicology Research, 2018 - academic.oup.com
Objective: To explore the effects of different dosages of 4-nonylphenol (4-NP) on the fatty
acid synthesis and estrogen receptor α (ERα) expression in the livers of F1 and F2 rats …

The adverse effects of perinatal exposure to nonylphenol on carbohydrate metabolism in male offspring rats

J Yang, J Yu, P Wang, Y Luo, XF Yang… - International Journal …, 2017 - Taylor & Francis
Background: We sought to investigate the adverse effects of perinatal exposure to
nonylphenol (NP) on carbohydrate metabolism of male offspring rats. Methods: Thirty-two …

Adverse effects of chronic exposure to nonylphenol on non-alcoholic fatty liver disease in male rats

J Yu, X Yang, Y Luo, X Yang, M Yang, J Yang, J Zhou… - PLoS …, 2017 - journals.plos.org
Endocrine-disrupting chemical (EDC) has been thought to play a role in non-alcoholic fatty
liver disease (NAFLD). However, the toxic effects of Nonylphenol (NP), an EDC, on non …

Perinatal exposure to 4-nonylphenol affects adipogenesis in first and second generation rats offspring

H Zhang, W Xue, Y Li, Y Ma, Y Zhu, W Huo, B Xu… - Toxicology letters, 2014 - Elsevier
Abstract Maternal exposure to 4-nonylphenol (4-NP) during pregnancy was shown to alter
adipogenesis in rodents, yet whether the effects are restricted to 4-NP-exposed offspring …

Nonylphenol aggravates non-alcoholic fatty liver disease in high sucrose-high fat diet-treated rats

J Yu, X Yang, X Yang, M Yang, P Wang, Y Yang… - Scientific reports, 2018 - nature.com
Exposure to environmental endocrine disruptors (EEDs) contributes to the pathogenesis of
many metabolic disorders. Here, we have analyzed the effect of the EED-nonylphenol (NP) …

[HTML][HTML] Effects of 4-nonylphenol on oxidant/antioxidant balance system inducing hepatic steatosis in male rat

A Kourouma, H Keita, P Duan, C Quan, KK Bilivogui… - Toxicology Reports, 2015 - Elsevier
An emerging literature suggests that early life exposure to 4-nonylphenol (4-NP), a
widespread endocrine disrupting chemical, may increase the risk of metabolic syndrome. In …

The effect of long-term exposure to nonylphenol at environmentally relevant levels on mouse liver and adipose tissue

CM Ribeiro, FCB de Oliveira, SA Pereira… - Environmental …, 2023 - Elsevier
Exposure to the xenoestrogen nonylphenol (NP) during critical windows of development
leads to metabolic abnormalities in adult life. However, less is known about NP exposure …

Non-alcoholic fatty liver disease induced by perinatal exposure to bisphenol a is associated with activated mTOR and TLR4/NF-κB signaling pathways in offspring rats

R Lin, D Wu, FJ Wu, Y Meng, JH Zhang… - Frontiers in …, 2019 - frontiersin.org
Accumulating evidence suggests a role of bisphenol A (BPA) in non-alcoholic fatty liver
disease (NAFLD), and its mechanism may be related to the up-regulation of lipogenic …