Mitochondrial dysfunction in early life resulted from perinatal bisphenol A exposure contributes to hepatic steatosis in rat offspring
Y Jiang, W Xia, Y Zhu, X Li, D Wang, J Liu, H Chang… - Toxicology letters, 2014 - Elsevier
An emerging literature suggests that bisphenol A (BPA), a widespread endocrine disrupting
chemical, when exposure occurs in early life, may increase the risk of metabolic syndrome …
chemical, when exposure occurs in early life, may increase the risk of metabolic syndrome …
Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet …
Developmental bisphenol A (BPA) exposure increases adulthood hepatic steatosis with
reduced mitochondrial function. To investigate the potential epigenetic mechanisms behind …
reduced mitochondrial function. To investigate the potential epigenetic mechanisms behind …
Different combinations of maternal and postnatal diet are reflected in changes of hepatic parenchyma and hepatic TNF-alpha expression in male rat offspring
Obesity is related to increased TNF-alpha production in different tissues. TNF-alpha is
connected to mitochondrial dysfunction in the liver and also development of fatty infiltration …
connected to mitochondrial dysfunction in the liver and also development of fatty infiltration …
3-tert-Butyl-4-hydroxyanisole Impairs Hepatic Lipid Metabolism in Male Mice Fed with a High-Fat Diet
Z Sun, Z Tang, X Yang, QS Liu, J Zhang… - Environmental …, 2022 - ACS Publications
3-tert-Butyl-4-hydroxyanisole (3-BHA), one of the widely used food antioxidants, has been
found to act as a potential obesogen by promoting adipogenesis in vitro and inducing white …
found to act as a potential obesogen by promoting adipogenesis in vitro and inducing white …
Di-2-ethylhexyl phthalate disrupts hepatic lipid metabolism in obese mice by activating the LXR/SREBP-1c and PPAR-α signaling pathways
X Liang, J Liang, S Zhang, H Yan, T Luan - Science of The Total …, 2024 - Elsevier
Abstract Di-2-ethylhexyl phthalate (DEHP), a widely utilized plasticizer, has been described
as a potential obesogen based on in vivo disruption of hepatic lipid homeostasis and in vitro …
as a potential obesogen based on in vivo disruption of hepatic lipid homeostasis and in vitro …
Neonatal exposure of bisphenol A led to increased lipolysis of visceral adipose tissue in adult rats with DNA hypomethylation of Atgl being one of the possible …
ZH Ke, AL Yu, XF Cai, Y Sun, HL Xu, M Chen, CX Chen… - Toxicology, 2022 - Elsevier
Accumulating evidence suggests the role of developmental exposure of bisphenol A (BPA)
in metabolic disorders. However, the underlying mechanism remains unclear. Using a rat …
in metabolic disorders. However, the underlying mechanism remains unclear. Using a rat …
Maternal resveratrol treatment re-programs and maternal high-fat diet-induced retroperitoneal adiposity in male offspring
TA Tsai, CK Tsai, LT Huang, JM Sheen… - International journal of …, 2020 - mdpi.com
Obesity during pregnancy increases the risk of cardiovascular problems, diabetes, asthma,
and cognitive impairments, affecting the offspring. It is important to reduce the negative …
and cognitive impairments, affecting the offspring. It is important to reduce the negative …
Maternal Low-Protein Diet during Puberty and Adulthood Aggravates Lipid Metabolism of Their Offspring Fed a High-Fat Diet in Mice
X Huang, Y Zhuo, D Jiang, Y Zhu, Z Fang, L Che, Y Lin… - Nutrients, 2022 - mdpi.com
A maternal low-protein (LP) diet during gestation and/or lactation results in metabolic
syndrome in their offspring. Here, we investigated the effect of maternal LP diet during …
syndrome in their offspring. Here, we investigated the effect of maternal LP diet during …
4-tert-Butylphenol impairs the liver by inducing excess liver lipid accumulation via disrupting the lipid metabolism pathway in zebrafish
H Wang, J Liu, S Qiang, Y Che, T Hu - Environmental Pollution, 2024 - Elsevier
Endocrine disrupting chemicals (EDCs) can disrupt normal endocrine function by interfering
with the synthesis and release of hormones, causing adverse reactions to development …
with the synthesis and release of hormones, causing adverse reactions to development …
Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway
This study aimed to evaluate female adult offspring induced by prenatal caffeine exposure
(PCE) are susceptible to non-alcoholic fatty liver disease (NAFLD) and to explore the …
(PCE) are susceptible to non-alcoholic fatty liver disease (NAFLD) and to explore the …