Paternal preconceptional supplementation of n‐3 polyunsaturated fatty acids alleviates offspring nonalcoholic fatty liver disease in high‐fat diet‐induced obese mice

Q Shi, X Fan, M Yang, T Tang, R Wang, P Li… - Food Frontiers, 2024 - Wiley Online Library
Exposure to nutritional or environmental factors in early life determines susceptibility to
nonalcoholic fatty liver disease (NAFLD). The effect of paternal preconceptional n‐3 …

[HTML][HTML] Prenatal bisphenol A exposure and postnatal trans fat diet alter small intestinal morphology and its global DNA methylation in male sprague-dawley rats …

S Zulkifli, NS Mohd Nor, SH Sheikh Abdul Kadir… - Nutrients, 2022 - mdpi.com
In this study, we aimed to determine whether a postnatal trans fat diet (TFD) could aggravate
prenatal bisphenol A (BPA) exposure effects on offspring's small intestine and adulthood …

Sub-chronically exposing mice to a polycyclic aromatic hydrocarbon increases lipid accumulation in their livers

Y Jin, W Miao, X Lin, T Wu, H Shen, S Chen, Y Li… - Environmental …, 2014 - Elsevier
The potential for exposing humans and wildlife to environmental polycyclic aromatic
hydrocarbons (PAHs) has increased. Risk assessments describing how PAHs disturb lipid …

Fish oil supplementation during pregnancy decreases liver endocannabinoid system and lipogenic markers in newborn rats exposed to maternal high-fat diet

LB Fassarella, JGO Neto, J Woyames… - European Journal of …, 2024 - Springer
Purpose Maternal high-fat diet (HF) programs obesity, metabolic dysfunction-associated
steatotic liver disease (MASLD), hypertriglyceridemia, and hyperglycemia associated with …

Perinatal nicotine exposure increases obesity susceptibility in adult male rat offspring by altering early adipogenesis

J Fan, W Zhang, Y Rao, J Xue, F Wang, L Zhang… - …, 2016 - academic.oup.com
The present study aims to evaluate whether perinatal nicotine (NIC) exposure increases
obesity susceptibility in adult male rat offspring by altering early adipogenesis. NIC was sc …

[HTML][HTML] Prenatal nicotine exposure enhances the susceptibility to metabolic syndrome in adult offspring rats fed high-fat diet via alteration of HPA axis-associated …

D Xu, L Xia, L Shen, Y Lei, L Liu, L Zhang… - Acta Pharmacologica …, 2013 - nature.com
Aim: Prenatal nicotine exposure (PNE) alters the hypothalamic-pituitary-adrenocortical
(HPA) axis-associated neuroendocrine metabolic programming in intrauterine growth …

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

A Hari, MDM AbdulHameed, MR Balik-Meisner… - Frontiers in …, 2024 - frontiersin.org
Toxicants with the potential to bioaccumulate in humans and animals have long been a
cause for concern, particularly due to their association with multiple diseases and organ …

A high‐fat, high‐fructose diet induces antioxidant imbalance and increases the risk and progression of nonalcoholic fatty liver disease in mice

K Jarukamjorn, N Jearapong, C Pimson… - …, 2016 - Wiley Online Library
Excessive fat liver is an important manifestation of nonalcoholic fatty liver disease (NAFLD),
associated with obesity, insulin resistance, and oxidative stress. In the present study, the …

Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood

MS Izadi, F Eskandari, F Binayi, M Salimi, FS Rashidi… - Life Sciences, 2022 - Elsevier
Aims The early postnatal dietary intake has been considered a crucial factor affecting the
offspring later life metabolic status. Consistently, this study investigated the oxidative and …

[HTML][HTML] Effects of BPA exposure and recovery on the expression of genes involved in the hepatic lipid metabolism in male mice

C Li, N Shen, S Yang, HL Wang - Toxics, 2023 - mdpi.com
Exposure to Bisphenol A (BPA) has led to an increased risk of obesity and nonalcoholic fatty
liver diseases (NAFLDs). However, it is as yet unclear if the damage caused by BPA is able …