[HTML][HTML] Caffeic acid and ellagic acid ameliorate adjuvant-induced arthritis in rats via targeting inflammatory signals, chitinase-3-like protein-1 and angiogenesis

EM Fikry, AM Gad, AH Eid, HH Arab - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory arthropathy that principally attacks the
joints. The present study aimed to explore the potential anti-arthritic effects of caffeic acid …

[HTML][HTML] Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes

X Huang, Y Xi, Q Pan, Z Mao, R Zhang, X Ma… - Biomedicine & …, 2018 - Elsevier
Osteoarthritis (OA) is a common articular disease that features cartilage loss and destruction.
It has been confirmed that inflammation plays major roles in the progression of osteoarthritis …

Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and …

Y Qu, Y Shen, L Teng, Y Huang, Y Yang, X Jian… - International …, 2022 - Elsevier
Osteoarthritis (OA) is the most common arthritis, and is characterized by inflammation and
cartilage degradation. Chicoric acid (CA), a bioactive caffeic acid derivative isolated from the …

Ellagic acid alleviates adjuvant induced arthritis by modulation of pro-and anti-inflammatory cytokines

G Allam, EA Mahdi, AM Alzahrani… - … European Journal of …, 2016 - termedia.pl
Abstract rheumatoid arthritis (ra) is a chronic inflammatory disease of unknown aetiology, but
it is now clear that pro-inflammatory cytokines play a central role in its pathogenesis. Ellagic …

Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways

R Lu, YG Wang, Y Qu, SX Wang, C Peng… - Bone & Joint …, 2023 - boneandjoint.org.uk
Aims Osteoarthritis (OA) is a prevalent joint disorder with inflammatory response and
cartilage deterioration as its main features. Dihydrocaffeic acid (DHCA), a bioactive …

Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway

W Sun, W Xie, D Huang, Y Cui… - International …, 2022 - spandidos-publications.com
Osteoarthritis (OA) is the most common degenerative disease affecting the joints, and
inflammation appears to play a critical role in the initiation and progression of OA. Caffeic …

Asiatic acid protects articular cartilage through promoting chondrogenesis and inhibiting inflammation and hypertrophy in osteoarthritis

Z Yang, L Feng, J Huang, X Zhang, W Lin… - European journal of …, 2021 - Elsevier
Natural small molecules have become attractive in osteoarthritis (OA) treatment. This study
aims to investigate the effect of asiatic acid (AA) on OA development in vitro and in vivo …

Quercetin alleviates osteoarthritis progression in rats by suppressing inflammation and apoptosis via inhibition of IRAK1/NLRP3 signaling

W Li, Y Wang, Y Tang, H Lu, Y Qi, G Li… - Journal of …, 2021 - Taylor & Francis
Introduction Quercetin was recently reported to help protect against osteoarthritis (OA)
progression, but the molecular mechanism for that protective affect remains unclear …

Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis

H Zhuang, X Ren, F Jiang, P Zhou - Molecular Medicine, 2023 - Springer
Background Osteoarthritis (OA) is a common chronic disease characterized by chronic
inflammation and extracellular matrix degradation. Indole-3-propionic acid (IPA) is a …

Anhuienoside C ameliorates collagen-induced arthritis through inhibition of MAPK and NF-κB signaling pathways

Q Liu, XH Xiao, LB Hu, HY Jie, Y Wang… - Frontiers in …, 2017 - frontiersin.org
Anemone flaccida Fr. Schmidt (Ranunculaceae)(Di Wu in Chinese) is used to treat punch
injuries and rheumatoid arthritis (RA). Our previous report has shown that crude triterpenoid …