Spontaneous remission of proteinuria is a frequent event in phospholipase A2 receptor antibody-negative patients with membranous nephropathy

E Hoxha, S Harendza, HO Pinnschmidt… - Nephrology Dialysis …, 2015 - academic.oup.com
Background Phospholipase A2 receptor antibodies (PLA2R-Ab) and thrombospondin type-1
domain-containing 7A antibodies (THSD7A-Ab) are present in 70–80% of patients with …

Clinical relevance of domain-specific phospholipase A2 receptor 1 antibody levels in patients with membranous nephropathy

L Reinhard, G Zahner, S Menzel… - Journal of the …, 2020 - journals.lww.com
Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …

Detection and clinical significance of glomerular M‐type phospholipase A2 receptor in patients with idiopathic membranous nephropathy

H Liu, W Luo, S Gong, X Ding - Internal Medicine Journal, 2016 - Wiley Online Library
Background Glomerular M‐type phospholipase A2 receptor (PLA2R) is important for
diagnosing idiopathic membranous nephropathy (IMN). The relation between glomerular …

[引用][C] Anti-phospholipase A2 receptor antibodies in primary membranous nephropathy—10 key points

EP McQuarrie - Nephrology Dialysis Transplantation, 2018 - academic.oup.com
Membranous nephropathy (MN) remains the most common primary cause of nephrotic
syndrome in Europe and a common cause of end-stage renal failure. The reporting of …

Anti–Phospholipase A2 Receptor 1 and Anti–Cysteine Rich antibodies, domain recognition and rituximab efficacy in membranous nephropathy: a prospective cohort …

P Ruggenenti, L Reinhard, B Ruggiero, A Perna… - American Journal of …, 2024 - Elsevier
Rationale & Objective Proteinuria and anti–phospholipase A 2 receptor 1 (anti-PLA 2 R1)
antibody titers are associated with primary membranous nephropathy (MN) outcomes. We …

Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy

Y Qin, Q Wu, H Sheng, T Li, X Liu, X Yang… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …

Diagnostic efficacy of serum anti-phospholipase A2 receptor antibodies for idiopathic membranous nephropathy in patients with diabetic kidney disease

Q Wang, Z Dong, W Zhang, X Liu, Y Qu, S Duan… - Clinica Chimica …, 2020 - Elsevier
Aim Serum anti-phospholipase A2 receptor (anti-PLA2R) antibodies are highly accurate in
diagnosing idiopathic membranous nephropathy (IMN) in populations with kidney disease …

Nephrotic syndrome: A new specific test for idiopathic membranous nephropathy

H Debiec, P Ronco - Nature Reviews Nephrology, 2011 - nature.com
Circulating anti-phospholipase A2 receptor (PLA2R) antibodies have been identified as an
immunological marker of disease activity in patients with idiopathic membranous …

Association of anti-PLA2R antibodies with outcomes after immunosuppressive therapy in idiopathic membranous nephropathy

AP Bech, JM Hofstra, PE Brenchley… - Clinical Journal of the …, 2014 - journals.lww.com
Background The optimal timing and duration of immunosuppressive therapy for idiopathic
membranous nephropathy (iMN) have been debated. This study aimed to evaluate whether …

[HTML][HTML] A new chemiluminescence immunoassay for phospholipase A2 receptor 1 autoantibodies allows early identification of autoantibody recurrence in patients …

E Hoxha, RAK Stahl, L Reinhard, A Kühnl… - Kidney International …, 2021 - Elsevier
Background Circulating autoantibodies against the M-type phospholipase A 2 receptor 1
(PLA 2 R1) are important biomarkers in membranous nephropathy (MN), supporting the …