Teleost fish are indispensable model organisms for comparative immunology research that
should lead to an improved understanding of the general principles of vertebrate immune …

The immune system is a complex and sophisticated biological system, spanning multiple
levels of complexity, from the molecular level to that of tissue. Our current understanding of …

Teleost adaptive immune systems have evolved with more flexibility than previously
assumed. A particularly enigmatic system to address immune system modifications in the …

The catfish industry is the largest sector of US aquaculture production. Given its role in food
production, the catfish immune response to industry-relevant pathogens has been …

The spleen is a conserved secondary lymphoid organ that emerged in parallel to adaptive
immunity in early jawed vertebrates. Recent studies have applied single cell transcriptomics …

The immune system of vertebrate species consists of many different cell types that have
distinct functional roles and are subject to different evolutionary pressures. Here, we first …

In vertebrates, bony fishes possess not only innate immune cells but also T and B cells that
are equivalent to those in mammals. However, the precise sub-cluster of immune cells in …

The zebrafish has proven to be a valuable model organism for studying hematopoiesis, but
relatively little is known about zebrafish immune cell development and functional diversity …

Fish is considered as a supreme model for clarifying the evolution and regulatory
mechanism of vertebrate immunity. However, the knowledge of distinct immune cell …

The risk and severity of pathogen infections in humans, livestock, or wild organisms depend
on host immune function, which can vary between closely related host populations or even …