The Relationship of MDR-1 Gene Expression and Chemotherapy Regimens in Acute Leukemia
T Bykova, A Sominskaya, I Stuif, N Anikina… - Gene Technology: Stem …, 1996 - Springer
Data about induction of MDR-1 gene expression usually are derived from in vitro studies.
Clinical data on the prognostic significance of MDR-1 gene expression in relation to the …
Clinical data on the prognostic significance of MDR-1 gene expression in relation to the …
[PDF][PDF] Semiquantitative RT-PCR evaluation of the MDR1 gene expression in patients with acute myeloid leukemia
Z Trnková, R Bedrlíková, J Marková… - NEOPLASMA …, 2007 - academia.edu
Resistance to chemotherapy is one of the major obstacles to effective treatment in acute
myeloid leukemia (AML). The most extensively studied protein involved in multidrug …
myeloid leukemia (AML). The most extensively studied protein involved in multidrug …
[引用][C] Development of a highly sensitive multiparameter flow cytometric assay correlating MDR1 expression and function: Clinical application to acute myeloid …
CP Leith, KJ Kopecky, IM Chen, FR Appelbaum… - Drug Resistance in …, 1997
MDR1/P-GP expression as a prognostic factor in acute leukemias
JP Marie, O Legrand - Drug Resistance in Leukemia and Lymphoma III, 1999 - Springer
Abstract P-glycoprotein (P-gp) is often expressed (40–50%) on leukemic cells at diagnosis
in acute myelogenous leukemia (AML), and is even more frequently present after treatment …
in acute myelogenous leukemia (AML), and is even more frequently present after treatment …
MDR1 (multidrug resistance) gene expression in adult acute leukemia: Correlations with blast phenotype.
H Miyachi, Y Takemura, S Yonekura… - International Journal …, 1993 - europepmc.org
Resistance to multiple chemotherapeutic agents is related to the production of P-
glycoprotein, a transmembrane drug efflux pump that is encoded by the multidrug resistance …
glycoprotein, a transmembrane drug efflux pump that is encoded by the multidrug resistance …
MDR 1 expression is an independent prognostic factor for response and survival in de novo acute myeloid leukaemia
MM Van Den Heuvel‐Eibrink… - British journal of …, 1997 - Wiley Online Library
The Multidrug Resistance gene (MDR 1) is frequently expressed in acute myeloid leukaemia
(AML). MDR 1 is associated with resistance to chemotherapy in vitro and with a poor …
(AML). MDR 1 is associated with resistance to chemotherapy in vitro and with a poor …
[PDF][PDF] Clinical Relevance of Multidrug Resistance Proteins Expression in Patients with de novo Acute Myeloid Leukaemia
E WOJDAT, K LENART, A SZYDA, O HAUS - dbc.wroc.pl
Background. Early occurrence of the multidrug resistance (MDR) in de novo acute myeloid
leukaemia (AML) may contribute to the treatment failure. Objectives. Prospective …
leukaemia (AML) may contribute to the treatment failure. Objectives. Prospective …
Flow cytometric assessment of multidrug resistance (MDR) phenotype in acute myeloid leukaemia
SM Hart, K Ganeshaguru, MPA Lyttelton… - Leukemia & …, 1993 - Taylor & Francis
Forty one patients with acute myeloid leukemia (AML), including 27 at presentation and 14
relapsed or resistant cases, were assessed for laboratory evidence of the MDR phenotype …
relapsed or resistant cases, were assessed for laboratory evidence of the MDR phenotype …