[HTML][HTML] Low-density lipoprotein particles in atherosclerosis

YN Qiao, YL Zou, SD Guo - Frontiers in Physiology, 2022 - frontiersin.org
Among the diseases causing human death, cardiovascular disease (CVD) remains number
one according to the World Health Organization report in 2021. It is known that …

Small dense low-density lipoprotein: Analytical review

C Kanonidou - Clinica Chimica Acta, 2021 - Elsevier
Background The causal relationship between low-density lipoprotein (LDL) and
atherosclerotic cardiovascular disease (CVD) has been firmly substantiated. LDL consists of …

[HTML][HTML] Association of small, dense LDL-cholesterol concentration and lipoprotein particle characteristics with coronary heart disease: a systematic review and meta …

L Liou, S Kaptoge - PloS one, 2020 - journals.plos.org
Objectives The aim of this study was to systematically collate and appraise the available
evidence regarding the associations between small, dense low-density lipoprotein (sdLDL) …

Low-density lipoprotein particle number and risk for cardiovascular disease

WC Cromwell, JD Otvos - Current atherosclerosis reports, 2004 - Springer
The key role played by low-density lipoprotein (LDL) particles in the pathogenesis of
coronary heart disease (CHD) is well accepted, as is the benefit of lowering LDL in high-risk …

Small dense low‐density lipoprotein as biomarker for atherosclerotic diseases

EA Ivanova, VA Myasoedova… - Oxidative medicine …, 2017 - Wiley Online Library
Low‐density lipoprotein (LDL) plays a key role in the development and progression of
atherosclerosis and cardiovascular disease. LDL consists of several subclasses of particles …

Small LDL-cholesterol is superior to LDL-cholesterol for determining severe coronary atherosclerosis

S Koba, Y Yokota, T Hirano, Y Ito, Y Ban… - … of atherosclerosis and …, 2008 - jstage.jst.go.jp
Aim: Recent evidence suggests that small dense low-density lipoprotein (sd-LDL) particles
are more atherogenic than large-LDL in spite of their lower cholesterol content. This study …

Clinical importance and therapeutic modulation of small dense low-density lipoprotein particles

IF Gazi, V Tsimihodimos, AD Tselepis… - Expert opinion on …, 2007 - Taylor & Francis
The National Cholesterol Education Programme Adult Treatment Panel III accepted the
predominance of small dense low-density lipoprotein (sdLDL) as an emerging …

Small dense low-density lipoprotein particles: clinically relevant?

RM Krauss - Current opinion in lipidology, 2022 - journals.lww.com
A growing body of data points to sdLDL concentration as a significant determinant of ASCVD
risk. Although future studies should be aimed at determining the clinical benefit of reducing …

Smallest LDL particles are most strongly related to coronary disease progression in men

PT Williams, HR Superko, WL Haskell… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—LDLs include particle subclasses that have different mobilities on polyacrylamide
gradient gels: LDL-I (27.2 to 28.5 nm), LDL-IIa (26.5 to 27.2 nm), LDL-IIb (25.6 to 26.5 nm) …

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

M Ruuth, SD Nguyen, T Vihervaara… - European heart …, 2018 - academic.oup.com
Aims Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease
(ASCVD) through their retention, modification, and accumulation within the arterial intima …