Extracellular vesicles in toxicological studies: key roles in communication between environmental stress and adverse outcomes

Y Qin, L Long, Q Huang - Journal of Applied Toxicology, 2020 - Wiley Online Library
External stressors, especially environmental toxicants can disturb biological homeostasis
and thus lead to adverse health effects. However, there is limited understanding of how cells …

Approaches to incorporate extracellular vesicles into exposure science, toxicology, and public health research

CK Carberry, D Keshava, A Payton, GJ Smith… - Journal of exposure …, 2022 - nature.com
Extracellular vesicles (EVs) represent small, membrane-enclosed particles that are derived
from parent cells and are secreted into the extracellular space. Once secreted, EVs can then …

Environmental exposures and extracellular vesicles: indicators of systemic effects and human disease

CM Eckhardt, AA Baccarelli, H Wu - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review Environmental pollutants contribute to the pathogenesis of
numerous diseases including chronic cardiovascular, respiratory, and neurodegenerative …

Seminar: extracellular vesicles as mediators of environmental stress in human disease

V Kalia, AA Baccarelli, C Happel… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Extracellular vesicles (EVs), membrane-bound particles containing a variety of
RNA types, DNA, proteins, and other macromolecules, are now appreciated as an important …

The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review

CK Carberry, JE Rager - Environmental and molecular …, 2023 - Wiley Online Library
Exposure to environmental chemicals is now well recognized as a significant factor
contributing to the global burden of disease; however, there remain critical gaps in …

Extracellular vesicles: how the external and internal environment can shape cell-to-cell communication

KY Neven, TS Nawrot, V Bollati - Current environmental health reports, 2017 - Springer
Purpose of the review To summarize the scientific evidence regarding the effects of
environmental exposures on extracellular vesicle (EV) release and their contents. As …

Extracellular vesicles under oxidative stress conditions: biological properties and physiological roles

E Chiaradia, B Tancini, C Emiliani, F Delo… - Cells, 2021 - mdpi.com
Under physio-pathological conditions, cells release membrane-surrounded structures
named Extracellular Vesicles (EVs), which convey their molecular cargo to neighboring or …

Exosomes in toxicology: relevance to chemical exposure and pathogenesis of environmentally linked diseases

DS Harischandra, S Ghaisas, D Rokad… - Toxicological …, 2017 - academic.oup.com
Chronic exposure to environmental toxins has been known to initiate or aggravate various
neurological disorders, carcinomas and other adverse health effects. Uptake by naïve cells …

Environmental pollutants and exosomes: A new paradigm in environmental health and disease

A Javdani-Mallak, I Salahshoori - Science of The Total Environment, 2024 - Elsevier
This study investigates the intricate interplay between environmental pollutants and
exosomes, shedding light on a novel paradigm in environmental health and disease …

Extracellular Vesicles: Footprints of environmental exposures in the aging process?

P Monti, G Solazzo, L Ferrari, V Bollati - Current Environmental Health …, 2021 - Springer
Purpose of the review Extracellular vesicles (EVs) are nano-sized lipid particles that
participate in intercellular signaling through the trafficking of bioactive molecules from …