Many chemicals in the environment mimic the female sex hormone, estrogen. Exposure to
environmental estrogens during early fetal development was proposed by Sharpe & …

The term environmental estrogen refers to chemical substances that exhibit some degree of
estrogen-like activity. The primary emphasis for potential adverse effects resulting from …

The synthetic estrogen diethylstilbestrol (DES) is a potent perinatal endocrine disrupter. In
humans and experimental animal models, exposure to DES during critical periods of …

The synthetic estrogen diethylstilbestrol (DES) is well documented to be a perinatal
carcinogen in both humans and experimental animals. Exposure to DES during critical …

Abstract Treatment of pregnant women with diethylstilbestrol (DES) is associated with the
subsequent development of reproductive tract abnormalities such as epididymal cysts …

The synthetic estrogen diethylstilbestrol (DES) is a potent perinatal endocrine disruptor. In
humans and experimental animals, exposure to DES during critical periods of reproductive …

Significant decreases in fertility have been observed over the past 50 years, with female
conception rates dropping by 44% and male sperm counts decreasing by over 50%. This …

Cryptorchidism and retention of Müllerian duct structures occur with high frequency among
the male offspring of CD-1 mice treated with 100 micrograms diethylstilbestrol/kg body …

This study assessed whether exposure of male rats to two estrogenic, environmental
chemicals, 4-octylphenol (OP) and butyl benzyl phthalate (BBP) during gestation or during …

Concerns have been raised regarding the role of environmental and dietary estrogens as
possible contributors to an increased incidence of various abnormalities in estrogen-target …