Remote limb ischemic conditioning during cerebral ischemia reduces infarct size through enhanced collateral circulation in murine focal cerebral ischemia

K Kitagawa, M Saitoh, K Ishizuka, S Shimizu - Journal of stroke and …, 2018 - Elsevier
Background Remote ischemic conditioning (RIC) induces protection in focal cerebral
ischemia. The conditioning is divided into pre-, per-, and postconditioning. However, the …

[HTML][HTML] Limb remote ischemic conditioning: mechanisms, anesthetics, and the potential for expanding therapeutic options

G Chen, M Thakkar, C Robinson, S Doré - Frontiers in neurology, 2018 - frontiersin.org
Novel and innovative approaches are essential in developing new treatments and improving
clinical outcomes in patients with ischemic stroke. Remote ischemic conditioning (RIC) is a …

Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke

MN Hoda, S Siddiqui, S Herberg… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Remote ischemic conditioning is cardioprotective in myocardial
infarction and neuroprotective in mechanical occlusion models of stroke. However, there is …

Remote limb ischemic postconditioning promotes motor function recovery in a rat model of ischemic stroke via the up‐regulation of endogenous tissue kallikrein

D Liang, XB He, Z Wang, C Li, BY Gao… - CNS neuroscience & …, 2018 - Wiley Online Library
Aims Remote ischemic conditionings, such as pre‐and per‐conditioning, are known to
provide cardioprotection in animal models of ischemia. However, little is known about the …

Remote ischemic post-conditioning improves neurological function by AQP4 down-regulation in astrocytes

S Li, X Hu, M Zhang, F Zhou, N Lin, Q Xia… - Behavioural brain …, 2015 - Elsevier
Cerebral ischemia is a primary cause of human death and long-term disability. Previous
studies have suggested that remote ischemic post-conditioning (RIPC) is a potential useful …

[HTML][HTML] Remote ischemic postconditioning ameliorates stroke injury via the SDF-1α/CXCR4 signaling axis in rats

G Jiang, X Li, M Liu, H Li, H Shen, W You, Q Fang… - Brain Research …, 2023 - Elsevier
Abstract Remote Ischemic Postconditioning (RIPostC) has become a research hotspot due
to its protective effect on the brain in clinical studies related to ischemic stroke. The purpose …

Remote Ischemic Conditioning After Stroke Trial 2: A Phase II b Randomized Controlled Trial in Hyperacute Stroke

TJ England, A Hedstrom, SE O'Sullivan… - Journal of the …, 2019 - Am Heart Assoc
Background Repeated episodes of limb ischemia and reperfusion (remote ischemic
conditioning [RIC]) may protect the brain from ischemic reperfusion injury. Methods and …

[HTML][HTML] Limb remote ischemic per-conditioning in combination with post-conditioning reduces brain damage and promotes neuroglobin expression in the rat brain …

C Ren, P Wang, B Wang, N Li, W Li… - Restorative …, 2015 - content.iospress.com
Purpose: Limb remote ischemic per-conditioning or post-conditioning has been shown to be
neuroprotective after cerebral ischemic stroke. However, the effect of combining remote per …

A multicenter, randomized trial on neuroprotection with remote ischemic per-conditioning during acute ischemic stroke: the REmote iSchemic Conditioning in acUtE …

F Pico, C Rosso, E Meseguer, ML Chadenat… - 2016 - journals.sagepub.com
Rationale Remote ischemic per-conditioning—causing transient limb ischemia to induce
ischemic tolerance in other organs—reduces final infarct size in animal stroke models. Aim …

AKT/GSK 3β‐dependent autophagy contributes to the neuroprotection of limb remote ischemic postconditioning in the transient cerebral ischemic rat model

ZF Qi, YM Luo, XR Liu, RL Wang… - CNS neuroscience & …, 2012 - Wiley Online Library
Background Limb remote ischemic postconditioning (RIP ost C) has been recognized as an
applicable strategy in protecting against cerebral ischemic injury. However, the time window …