AKT/GSK 3β‐dependent autophagy contributes to the neuroprotection of limb remote ischemic postconditioning in the transient cerebral ischemic rat model

ZF Qi, YM Luo, XR Liu, RL Wang… - CNS neuroscience & …, 2012 - Wiley Online Library
Background Limb remote ischemic postconditioning (RIP ost C) has been recognized as an
applicable strategy in protecting against cerebral ischemic injury. However, the time window …

Remote ischemic per-conditioning: a novel therapy for acute stroke?

CD Hahn, C Manlhiot, MR Schmidt, TT Nielsen… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Remote ischemic preconditioning is a phenomenon by which a
short period of sublethal ischemia to an organ protects against subsequent ischemia in …

A meta-analysis of remote ischaemic conditioning in experimental stroke

P Weir, R Maguire, SE O'Sullivan… - Journal of Cerebral …, 2021 - journals.sagepub.com
Remote ischaemic conditioning (RIC) is achieved by repeated transient ischaemia of a
distant organ/limb and is neuroprotective in experimental ischaemic stroke. However, the …

Platelet‐derived microparticles are implicated in remote ischemia conditioning in a rat model of cerebral infarction

LY Shan, JZ Li, LY Zu, CG Niu, A Ferro… - CNS neuroscience & …, 2013 - Wiley Online Library
Aim Remote ischemic preconditioning protects against ischemic organ damage by giving
short periods of subcritical ischemia to a remote organ. We tested the hypothesis that remote …

Remote ischemic preconditioning‐mediated neuroprotection against stroke is associated with significant alterations in peripheral immune responses

ZJ Liu, C Chen, XR Li, YY Ran, T Xu… - CNS neuroscience & …, 2016 - Wiley Online Library
Aims Remote ischemic preconditioning (RIPC) of a limb is a clinically feasible strategy to
protect against ischemia–reperfusion injury after stroke. However, the mechanism …

Remote ischemic conditioning for acute ischemic stroke: dawn in the darkness

J Pan, X Li, Y Peng - Reviews in the Neurosciences, 2016 - degruyter.com
Stroke is a leading cause of disability with high morbidity and mortality worldwide. Of all
strokes, 87% are ischemic. The only approved treatments for acute ischemic stroke are …

Remote but not distant: a review on experimental models and clinical trials in remote ischemic conditioning as potential therapy in ischemic stroke

I Mollet, JP Marto, M Mendonça, MV Baptista… - Molecular …, 2022 - Springer
Stroke is one of the main causes of neurological disability worldwide and the second cause
of death in people over 65 years old, resulting in great economic and social burden …

Remote ischemic postconditioning for ischemic stroke: a systematic review and meta-analysis of randomized controlled trials

JJ Zhao, H Xiao, WB Zhao, XP Zhang… - Chinese Medical …, 2018 - mednexus.org
Background: Remote ischemic postconditioning (RIPostC) appears to protect distant organs
from ischemia-reperfusion injury (IRI). However, cerebral protection results have remained …

Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning

C Ren, X Gao, GK Steinberg, H Zhao - Neuroscience, 2008 - Elsevier
Remote ischemic preconditioning is an emerging concept for stroke treatment, but its
protection against focal stroke has not been established. We tested whether remote …

Remote limb ischemic preconditioning protects rats against cerebral ischemia via HIF-1α/AMPK/HSP70 pathway

M Xia, Q Ding, Z Zhang, Q Feng - Cellular and molecular neurobiology, 2017 - Springer
Remote limb ischemic preconditioning (RIPC) is a clinically feasible strategy to protect
against ischemia/reperfusion injury, but the knowledge concerning the mechanism …