Angiotensin-converting enzyme (ACE) inhibitors can reduce cardiac mass in both clinical
and experimental cardiac hypertrophy. Because cytoplasmic Na+ and pH have been …

The increase in plasma renin activity after angiotensin I-converting enzyme inhibition by
Captopril (SQ 14225) is well documented. In a study of the mechanism of Captopril-induced …

1. Changes in arterial blood pressure, blood angiotensin I, plasma angiotensin II and
plasma angiotensin III were measured in conscious sodium-depleted dogs after infusion of …

In rats treated continuously with captopril (80 μg/h, ip), for 2 days, blood pressure decreased
and adrenal angiotensin II receptor concentration was decreased from 160 fmol/mg protein …

The evaluation of a new drug in normotensive volunteers can provide important information,
as long as the compound has a specific mechanism of action which can be evaluated in …

Abstract 1 The renal haemodynamic responses to a close arterial infusion of noradrenaline
(29.7-177.9 nmol kg-1 h-1) were measured in rats anaesthetized with pentobarbitone …

The role of the renin-angiotensin system in the pathogenesis of one-clip, two-kidney
hypertension has been studied in man, dog and rat. Particular attention has been paid to …

Methods Studies were conducted in 47 male Sprague-Dawley rats, each weighing 280 to
480 g, that were fed a low sodium diet containing less than 5 mmoles of sodium per kilogram …

Effects of angiotensin infusion on renal function in the unanesthetized rat Page 1
AMERICAN JOURNAL OF PHYSIOLOGY Vol. 213, No. 5, November 1967. Printed in USA …

Previous studies have indicated that intrarenal converting enzyme (CE) inhibition had no
influence on renal blood flow (RBF). The present study examined the effect of intrarenal CE …