Frontiers in genomic assay technologies: the grand challenges in enabling data-intensive biological research

DW Galbraith - Frontiers in Genetics, 2011 - frontiersin.org
We live in astonishing times, not least when we consider the recent rate of progress in
science. We are experiencing a revolution, underpinned and empowered by Moore's …

Nucleic acid-based diagnostics for infectious diseases in public health affairs

ACH Yu, G Vatcher, X Yue, Y Dong, MH Li… - Frontiers of …, 2012 - Springer
Infectious diseases, mostly caused by bacteria and viruses but also a result of fungal and
parasitic infection, have been one of the most important public health concerns throughout …

Noninstrumented nucleic acid amplification assay

BH Weigl, G Domingo, J Gerlach… - Microfluidics …, 2008 - spiedigitallibrary.org
We have developed components of a diagnostic disposable platform that has the dual
purpose of providing molecular diagnostics at the point of care (POC) as well as stabilizing …

Key issues, challenges, and future opportunities in gene quantification

F Ferré - Gene Quantification, 1998 - Springer
Perhaps it should be called an" end of the millennium" phenomenon, but it seems as if the
world is entangled in a quantitative frenzy. From the unresolved calculation of the rate of …

The implications of ENCODE for diagnostics

E Fratkin, S Bercovici, DA Stephan - Nature biotechnology, 2012 - nature.com
The implications of ENCODE for diagnostics | Nature Biotechnology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

2012 highlights in translational'omics

C Auffray, T Caulfield, MJ Khoury, JR Lupski… - Genome medicine, 2013 - Springer
Genomics Network completed its second cycle with a scientific symposium in Rome, Italy
[13]. What has the past 15 years produced, and where are we going next? A major …

Nanoswitch-linked immunosorbent assay (NLISA) for fast, sensitive, and specific protein detection

CH Hansen, D Yang, MA Koussa… - Proceedings of the …, 2017 - National Acad Sciences
Protein detection and quantification play critical roles in both basic research and clinical
practice. Current detection platforms range from the widely used ELISA to more …

Regulatory issues for genetic testing in clinical practice

U Kristoffersson - Molecular biotechnology, 2008 - Springer
Whereas deliver of health care is nationally based with great differences in ways of service
provision and financing between countries, and thus not subject to international regulations …

[图书][B] Next generation sequencing technologies in medical genetics

CA Valencia, MA Pervaiz, A Husami, Y Qian, K Zhang - 2013 - Springer
The purpose of this book is to serve as an introduction to those that want to learn about next-
generation–sequencing (NGS) and its applications. However, from the middle to end of each …

Shedding light on health and disease using molecular beacons

A Tsourkas, G Bao - Briefings in Functional Genomics, 2003 - academic.oup.com
The detection and identification of pathogens is often painstaking due to the low abundance
of diseased cells in clinical samples. The genomic sequences of the pathogen can be …