mRNA expression of tachykinins and tachykinin receptors in different human tissues

FM Pinto, TA Almeida, M Hernandez, P Devillier… - European journal of …, 2004 - Elsevier
The tachykinins substance P, neurokinin A and neurokinin B are involved in many
pathophysiological processes. A reverse transcription–polymerase chain reaction (RT-PCR) …

Tachykinins and tachykinin receptors: a growing family

JN Pennefather, A Lecci, ML Candenas, E Patak… - Life sciences, 2004 - Elsevier
The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

Tachykinins: receptor to effector

AM Khawaja, DF Rogers - The international journal of biochemistry & cell …, 1996 - Elsevier
Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature

R Patacchini, A Lecci, P Holzer, CA Maggi - Trends in Pharmacological …, 2004 - cell.com
The tachykinin family has recently been extended by the discovery of a third tachykinin gene
encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and …

Identification of a tachykinin NK2 receptor splice variant and its expression in human and rat tissues

ML Candenas, CG Cintado, JN Pennefather… - Life sciences, 2002 - Elsevier
The tachykinins substance P, neurokinin A and neurokinin B are implicated in different
diseases and play an important role in neuroimmunomodulation. These peptides interact …

The tachykinin NK1 receptor in the brain: pharmacology and putative functions

A Saria - European journal of pharmacology, 1999 - Elsevier
After its discovery in 1931, substance P (SP) remained the only mammalian member of the
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …

Peripheral tachykinin receptors as targets for new drugs

R Patacchini, CA Maggi - European journal of pharmacology, 2001 - Elsevier
Tachykinins are widely distributed in the peripheral nervous system of the respiratory,
urinary and gastrointestinal tract, stored in enteric neurons and in peripheral nerve endings …

New challenges in the study of the mammalian tachykinins

NM Page - Peptides, 2005 - Elsevier
There is an expanding repertoire of mammalian tachykinins produced by a variety of
tachykinin genes, gene splicing events and peptide processing. Novel tachykinin-binding …

Pharmacological profile of hemokinin 1: a novel member of the tachykinin family

V Camarda, A Rizzi, G Calo, R Guerrini, S Salvadori… - Life sciences, 2002 - Elsevier
Recently, the cloning of a novel preprotachykinin gene (PPT-C) has been reported. This
gene codes for a novel peptide named hemokinin 1 (HK-1). In contrast with the known …

Tachykinins and tachykinin receptors: structure and activity relationships

TA Almeida, J Rojo, PM Nieto, FM Pinto… - Current medicinal …, 2004 - ingentaconnect.com
In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …