[PDF][PDF] Artabotryside A, a constituent from Descurainia sophia (L.) induces cell death in U87 glioma cells through apoptosis and cell cycle arrest at G2/M phase

M Khan, Y Xiao, B Yu, N Wang, A Rasul, F Yi… - J Med Plants …, 2012 - academicjournals.org
Descurainia sophia (L.) commonly known as Webb ex Prantl (flixweed) is a Chinese
traditional medicinal plant. Seeds of flixweed are used in the treatment of some cancers …

[HTML][HTML] Induction of G2/M arrest and apoptosis through mitochondria pathway by a dimer sesquiterpene lactone from Smallanthus sonchifolius in HeLa cells

Y Kitai, X Zhang, Y Hayashida, Y Kakehi… - journal of food and drug …, 2017 - Elsevier
Dimer sesquiterpene lactones (SLs), uvedafolin and enhydrofolin, against four monomer
SLs isolated from yacon, Smallanthus sonchifolius, leaf were the most cytotoxic substances …

Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model

JY Hwang, JH Park, MJ Kim, WJ Kim, KT Ha, BT Choi… - Cancer Letters, 2019 - Elsevier
Glioblastoma multiforme (GBM) is the most common malignant brain tumor, which remains
incurable. Plant extracts are a potential source of potent anticancer medicines. In this study …

Davidone C induces the death of hepatocellular carcinoma cells by promoting apoptosis and autophagy

P Song, H Huang, Y Ma, C Wu, X Yang, HY Choi - Molecules, 2021 - mdpi.com
Davidone C is a newly discovered flavonoid compound purified from the ethyl acetate-
soluble fraction of Sophora davidii (Franch.) Skeels. This study explored the anti-tumor …

Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro

LR Sousa, AGS Oliveira, A Arantes, JGM Junqueira… - Molecules, 2023 - mdpi.com
Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection,
radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the …

Decursin induces apoptosis in glioblastoma cells, but not in glial cells via a mitochondria-related caspase pathway

ST Oh, S Lee, C Hua, BS Koo, SC Pak… - The Korean Journal …, 2019 - synapse.koreamed.org
Decursin is a major biological active component of Angelica gigas Nakai and is known to
induce apoptosis of metastatic prostatic cancer cells. Recently, other reports have been …

Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells

HS Song, S Jang, SC Kang - Phytomedicine, 2018 - Elsevier
Background Cullen corylifolium is a plant widely used in traditional Chinese medicine for its
stomachic, anthelmintic, and diuretic properties. Bavachalcone, which is known as a …

Dehydroeburicoic acid induces calcium-and calpain-dependent necrosis in human U87MG glioblastomas

JY Deng, SJ Chen, GM Jow, CW Hsueh… - Chemical research in …, 2009 - ACS Publications
Dehydroeburicoic acid (DeEA) is a triterpene purified from medicinal fungi such as Antrodia
camphorate, the crude extract of which is known to exert cytotoxic effects against several …

Severibuxine, Isolated from Severinia buxifolia, Induces Apoptosis in HL-60 Leukemia Cells

C Ito, T Murata, M Kato, N Suzuki… - Natural Product …, 2013 - journals.sagepub.com
In an ongoing search for cancer-preventing compounds derived from plant sources, we
isolated the quinolin-2, 4-dione alkaloid severibuxine from the root bark of Severinia …

[HTML][HTML] The n-Butanol Extract Obtained from the Inner Bark of Tabebuia rosea (Bertol.) DC, Specioside, and Catalposide Induce Leukemia Cell Apoptosis in the …

NY Guerrero-Pepinosa, LA Veloza… - Molecules, 2024 - mdpi.com
The cell signaling pathways involved in the antiproliferative activities of T. rosea inner bark
remain unexplored. This study evaluated the apoptotic effects of two iridoids from the inner …