Mapping how local perturbations influence systems-level brain dynamics
The human brain exhibits a distinct spatiotemporal organization that supports brain function
and can be manipulated via local brain stimulation. Such perturbations to local cortical …
and can be manipulated via local brain stimulation. Such perturbations to local cortical …
Relations between large-scale brain connectivity and effects of regional stimulation depend on collective dynamical state
L Papadopoulos, CW Lynn, D Battaglia… - PLoS computational …, 2020 - journals.plos.org
At the macroscale, the brain operates as a network of interconnected neuronal populations,
which display coordinated rhythmic dynamics that support interareal communication …
which display coordinated rhythmic dynamics that support interareal communication …
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics
Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …
response properties of neurons are dynamically modulated to support adaptive cognitive …
[HTML][HTML] New perspectives on dimensionality and variability from large-scale cortical dynamics
TA Engel, NA Steinmetz - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Large-scale cortical recordings reveal spontaneous dynamics on local and global
scales.•Inferred dimensionality may depend on the spatial scales of dynamics and …
scales.•Inferred dimensionality may depend on the spatial scales of dynamics and …
Sensory-motor cortices shape functional connectivity dynamics in the human brain
Large-scale biophysical circuit models provide mechanistic insights into the micro-scale and
macro-scale properties of brain organization that shape complex patterns of spontaneous …
macro-scale properties of brain organization that shape complex patterns of spontaneous …
[HTML][HTML] Transcranial direct current stimulation changes resting state functional connectivity: A large-scale brain network modeling study
Transcranial direct current stimulation (tDCS) is a noninvasive technique for affecting brain
dynamics with promising application in the clinical therapy of neurological and psychiatric …
dynamics with promising application in the clinical therapy of neurological and psychiatric …
[HTML][HTML] Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics
The large-scale organization of dynamical neural activity across cortex emerges through
long-range interactions among local circuits. We hypothesized that large-scale dynamics are …
long-range interactions among local circuits. We hypothesized that large-scale dynamics are …
Changes in cognitive state alter human functional brain networks
MN Moussa, CD Vechlekar, JH Burdette… - Frontiers in human …, 2011 - frontiersin.org
The study of the brain as a whole system can be accomplished using network theory
principles. Research has shown that human functional brain networks during a resting state …
principles. Research has shown that human functional brain networks during a resting state …
Stimulation-based control of dynamic brain networks
The ability to modulate brain states using targeted stimulation is increasingly being
employed to treat neurological disorders and to enhance human performance. Despite the …
employed to treat neurological disorders and to enhance human performance. Despite the …
Noninvasive brain stimulation: from physiology to network dynamics and back
Noninvasive brain stimulation techniques have been widely used for studying the
physiology of the CNS, identifying the functional role of specific brain structures and, more …
physiology of the CNS, identifying the functional role of specific brain structures and, more …