Ischemia‐modified albumin: origins and clinical implications

A Shevtsova, I Gordiienko, V Tkachenko… - Disease …, 2021 - Wiley Online Library
Albumin is one of the most abundant proteins in the body of mammals: about 40% of its pool
is located in the intravascular space and the remainder is found in the interstitial space. The …

Ischemia modified albumin: a novel biomarker for the detection of cardiac ischemia

DC Gaze - Drug metabolism and pharmacokinetics, 2009 - Elsevier
The diagnosis of cardiac ischemia remains a challenge in contemporary emergency
medicine. A blood-borne biomarker is an attractive alternative to cardiac imaging or stress …

[PDF][PDF] Ischemia modified albumin: is this marker of ischemia ready for prime time use

E Sbarouni, P Georgiadou, DT Kremastinos… - Hellenic J …, 2008 - hellenicjcardiol.org
First identified in the early 1990s, IMA is produced when ischemia stresses released from
hypoxic heart tissue induce modification of circulating albumin. 5, 6 The amino terminal end …

Ischemia modified albumin changes–review and clinical implications

E Sbarouni, P Georgiadou, V Voudris - Clinical Chemistry and …, 2011 - degruyter.com
Ischemia modified albumin (IMA), as measured using the albumin cobalt binding test, is
currently the most promising biomarker for early detection of ischemia before the onset of …

Albumin cobalt binding and ischemia modified albumin generation: an endogenous response to ischemia?

G Lippi, M Montagnana… - International …, 2006 - internationaljournalofcardiology.com
Myocardial ischemia has become the leading cause of mortality in western countries and
this unfavorable trend is unlikely to reverse in the near future. The events progression …

High ischemia-modified albumin concentration reflects oxidative stress but not myocardial involvement in systemic sclerosis

D Borderie, Y Allanore, C Meune, JY Devaux… - Clinical …, 2004 - academic.oup.com
Systemic sclerosis (SSc) is a connective tissue disease characterized by widespread
vascular lesions and fibrosis of the skin and internal organs. In SSc, vasospasm causes …

Ischemia-modified albumin concentrations in patients with peripheral vascular disease and exercise-induced skeletal muscle ischemia

D Roy, J Quiles, R Sharma, M Sinha… - Clinical …, 2004 - academic.oup.com
Background: Ischemia-modified albumin (IMA) is a new marker of myocardial ischemia,
there is concern that IMA concentrations may be affected by ischemia occurring in tissues …

Association between ischemia-modified albumin, lipids and inflammation biomarkers in patients with hypercholesterolemia

MMMF Duarte, JBT Rocha, RN Moresco, T Duarte… - Clinical …, 2009 - Elsevier
OBJECTIVES: The aim of this study was to evaluate the association between ischemia-
modified albumin (IMA), lipids and inflammation biomarkers in patients with …

Ischemia-modified albumin during skeletal muscle ischemia

E Zapico-Muñiz, M Santaló-Bel… - Clinical …, 2004 - academic.oup.com
Ischemia-modified albumin (IMA) has been proposed as a biological marker of myocardial
ischemia (1, 2). Exposure to ischemic myocardium modifies circulating albumin at its NH2 …

Ischemia-modified albumin levels in cerebrovascular accidents

A Gunduz, S Turedi, A Mentese, V Altunayoglu… - The American journal of …, 2008 - Elsevier
Background Previous studies have demonstrated that ischemia-modified albumin (IMA) is a
useful marker for the diagnosis of ischemic events. It was also recently demonstrated that …