Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Although amiodarone is regarded as a highly effective anti-arrhythmic agent, its use may
lead to alterations in thyroid gland function and/or thyroid hormone metabolism, partly …

Amiodarone is an antiarrhythmic agent with high iodine content. Ten patients treated with
amiodarone developed thyrotoxicosis. I 131 uptakes were negligible, and TT 3 levels low in …

Amiodarone-induced thyrotoxicosis: a difficult diagnostic and therapeutic challenge* Page 1
Clinical Endocrinology (2002) 56, 23–24 © 2002 Blackwell Science Ltd 23 Blackwell Science …

Cases of hypothyroidism and hyperthyroidism associated with amiodarone therapy are
described, and the mechanisms, clinical appearance, and management of amiodarone …

Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone has been reported as an anti-anginal drug in 19h7 [11 and as an anti-
arrhythmic drug in 1969 [2]. Thyroid side-effects (hypothyroidism and thyrotoxicosis) were …

Amiodarone, a benzofuranic-derivative iodine-rich drug used mostly for tachyarrhythmias,
often causes changes in the peripheral metabolism of thyroid hormones mainly due to the …

The author presents his experience with the thyroid complications of amiodarone therapy:
exceptional but sometimes serious conditions. Both, hypo-and hyperthyroidism can occur …

• Amiodarone is a widely used antiarrhythmic drug, which contains 75 mg of iodide per 200
mg of active substance. Eight of our patients receiving long-term amiodarone therapy …