Fibroblast growth factors (FGFs) are a versatile family of peptide growth factors that are
involved in various biological functions, including cell growth and differentiation, embryonic …

Macrophages make up a crucial aspect of the immune system, carrying out a variety of
functions ranging from clearing cellular debris to their well-recognized roles as innate …

Objective and design Compelling evidence indicates that dysregulated macrophages may
play a key role in driving inflammation in inflammatory bowel disease (IBD). Fibroblast …

Macrophages have a central role in numerous physiological processes, such as immune
defense, maintenance of tissue homeostasis, wound healing, and inflammation. Moreover …

Fibrinogen-like protein 2 (Fgl2) is critical for immune regulation in the inflammatory state.
Elevated Fgl2 levels are observed in patients with inflammatory bowel disease (IBD), but …

Regulation of the programming of tumour-associated macrophages (TAMs) controls tumour
growth and anti-tumour immunity. We examined the role of FGF2 in that regulation. Tumours …

The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the
ability to differentiate macrophages (MØs) with opposing functions, namely proinflammatory …

Monocytes/macrophages are heterogeneous and versatile cells that could undergo their
phenotypically/functionally dynamic switch in response to the microenvironment signals …

Fibrosis can occur in all major organs with relentless progress, ultimately leading to organ
failure and potentially death. Unfortunately, current clinical treatments cannot prevent or …

Fibrosis is commonly regarded as a pathological and dynamic process with the hallmarks of
chronic inflammation and wound healing. Emerging evidence indicates that heterogeneous …