While surgery plays a central role in the management of all stages of operable rectal cancer,
nonoperative approaches for both early-stage and locally advanced disease are being …

Nonoperative management of rectal cancer is an emerging treatment approach that aims to
enable carefully selected patients to avoid the morbidity of radical surgical resection, while …

Aim The standard treatment for low rectal cancer is preoperative chemoradiotherapy
followed by surgery with low anterior resection with diverting ileostomy or abdominoperineal …

The widespread use of neoadjuvant therapies has introduced a new variable, tumor
response, which may dramatically change the ultimate surgical decision from radical surgery …

Aim: Recent studies have piloted a nonoperative approach in patients with a complete
clinical response to neoadjuvant chemoradiation for non-metastatic rectal cancer. This study …

Surgery has long been the primary curative modality for localized rectal cancer.
Neoadjuvant chemoradiation has significantly improved local control rates and, in a …

In the last 250 years, the treatment of rectal cancer has changed dramatically. Once
considered an incurable disease, combined modality therapy has improved mortality from …

Rectal cancer affects more than 40,000 people in the United States annually. Despite recent
advances in radiation and chemotherapy, surgical resection remains an integral part of …

Surgery for rectal cancer has advanced greatly over the past decade. Our knowledge of total
mesorectal excision has led to improved oncologic outcomes. The concept of extralevator …

The management of rectal cancer has undergone significant changes over the past 50
years, and this has been associated with major improvements in overall outcomes and …