[HTML][HTML] Role of phenolic compounds in human disease: current knowledge and future prospects

MM Rahman, MS Rahaman, MR Islam, F Rahman… - Molecules, 2021 - mdpi.com
Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …

Intracellular signaling pathways modulated by phenolic compounds: application for new anti-inflammatory drugs discovery

G Costa, V Francisco, MC Lopes… - Current medicinal …, 2012 - ingentaconnect.com
Extensive research within the last two decades revealed that most chronic illnesses,
including cancer, neurological, autoimmune and cardiovascular diseases are mediated …

[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy

W Liu, X Cui, Y Zhong, R Ma, B Liu, Y Xia - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Natural phenolic compounds as cardiovascular therapeutics: potential role of their antiinflammatory effects

F Jiang, GJ Dusting - Current vascular pharmacology, 2003 - ingentaconnect.com
A number of epidemiological studies have shown that diets rich in plant-derived phenolic
compounds reduce the risk of coronary heart disease. The chronic antioxidant and …

Oxidative stress and inflammation: what polyphenols can do for us?

T Hussain, B Tan, Y Yin, F Blachier… - Oxidative medicine …, 2016 - Wiley Online Library
Oxidative stress is viewed as an imbalance between the production of reactive oxygen
species (ROS) and their elimination by protective mechanisms, which can lead to chronic …

Therapeutic potential of dietary phenolic acids

V Saibabu, Z Fatima, LA Khan… - … in Pharmacological and …, 2015 - Wiley Online Library
Although modern lifestyle has eased the quality of human life, this lifestyle's related patterns
have imparted negative effects on health to acquire multiple diseases. Many synthetic drugs …

Phenolic compounds: A good choice against chronic degenerative diseases

ML Luna-Guevara, JJ Luna-Guevara… - Studies in natural …, 2018 - Elsevier
Phenolic compounds are a group of metabolites derived from the secondary pathways of
plants. Polyphenols comprise flavonoids, phenolic acids, tannins, lignans, and coumarins …

[HTML][HTML] Pharmacological properties of polyphenols: Bioavailability, mechanisms of action, and biological effects in in vitro studies, animal models, and humans

K Stromsnes, R Lagzdina, G Olaso-Gonzalez… - Biomedicines, 2021 - mdpi.com
Drugs are bioactive compounds originally discovered from chemical structures present in
both the plant and animal kingdoms. These have the ability to interact with molecules found …

Basic biochemical mechanisms behind the health benefits of polyphenols

CG Fraga, M Galleano, SV Verstraeten… - Molecular aspects of …, 2010 - Elsevier
Polyphenols and consequently many flavonoids have several beneficial actions on human
health. However, the actual molecular interactions of polyphenols with biological systems …

The effects of polyphenols on oxidative stress and the arachidonic acid cascade. Implications for the prevention/treatment of high prevalence diseases

MT Mitjavila, JJ Moreno - Biochemical pharmacology, 2012 - Elsevier
Redox state unbalance and the activation of the arachidonic acid (AA) cascade, contribute to
the pathogenesis of cardiovascular disease (CVD) and cancer. Inflammatory cells that …