Genetics of thoracic and abdominal aortic diseases: aneurysms, dissections, and ruptures
Dissections or ruptures of aortic aneurysms remain a leading cause of death in the
developed world, with the majority of deaths being preventable if individuals at risk are …
developed world, with the majority of deaths being preventable if individuals at risk are …
Genetic and epigenetic regulation of aortic aneurysms
HW Kim, BK Stansfield - BioMed Research International, 2017 - Wiley Online Library
Aneurysms are characterized by structural deterioration of the vascular wall leading to
progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often …
progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often …
The genetic basis for aortic aneurysmal disease
A Saratzis, MJ Bown - Heart, 2014 - heart.bmj.com
Aortic aneurysms are an important cause of cardiovascular death in elderly patients. At
present, little is known of the pathobiology of aneurysmal disease and this limits the ability to …
present, little is known of the pathobiology of aneurysmal disease and this limits the ability to …
Opportunities in abdominal aortic aneurysm research: epidemiology, genetics, and pathophysiology
H Kuivaniemi, JR Elmore - Annals of vascular surgery, 2012 - Elsevier
Aortic aneurysms are a complex genetic disorder with known environmental risk factors such
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …
Genetics of abdominal aortic aneurysm
J Golledge, H Kuivaniemi - Current opinion in cardiology, 2013 - journals.lww.com
Genetics of abdominal aortic aneurysm : Current Opinion in Cardiology Genetics of abdominal
aortic aneurysm : Current Opinion in Cardiology Log in or Register Subscribe to journalSubscribe …
aortic aneurysm : Current Opinion in Cardiology Log in or Register Subscribe to journalSubscribe …
Hereditary influence in thoracic aortic aneurysm and dissection
Thoracic aortic aneurysm is a potentially life-threatening condition in that it places patients at
risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis …
risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis …
Genetics and mechanisms of thoracic aortic disease
Aortic disease has many forms including aortic aneurysm and dissection, aortic coarctation
or abnormalities in aortic function, such as loss of aortic distensibility. Genetic analysis in …
or abnormalities in aortic function, such as loss of aortic distensibility. Genetic analysis in …
Clinical validity of genes for heritable thoracic aortic aneurysm and dissection
Background: Thoracic aortic aneurysms progressively enlarge and predispose to acute
aortic dissections. Up to 25% of individuals with thoracic aortic disease harbor an underlying …
aortic dissections. Up to 25% of individuals with thoracic aortic disease harbor an underlying …
[HTML][HTML] The genetics and genomics of thoracic aortic disease
P Pomianowski, JA Elefteriades - Annals of cardiothoracic surgery, 2013 - ncbi.nlm.nih.gov
Genetic studies over the past several decades have helped to better elucidate the genomics
and inheritance of thoracic aortic diseases. Seminal work from various researchers have …
and inheritance of thoracic aortic diseases. Seminal work from various researchers have …
The genetics and typical traits of thoracic aortic aneurysm and dissection
J Rodrigues Bento, J Meester, I Luyckx… - Annual review of …, 2022 - annualreviews.org
Genetic predisposition and risk factors such as hypertension and smoking can instigate the
development of thoracic aortic aneurysm (TAA), which can lead to highly lethal aortic wall …
development of thoracic aortic aneurysm (TAA), which can lead to highly lethal aortic wall …