Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …

The care of patients with acute kidney injury (AKI) has been limited due to the lack of
effective therapeutics that can either prevent AKI during high-risk situations or treat AKI once …

Acute kidney injury (AKI) is a significant source of morbidity and mortality in pediatric
patients, affecting more than one quarter of critically ill children. Despite significant need …

Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the
high prevalence and high mortality rate of AKI, the development of drugs to effectively treat …

Current strategies to limit the extent of injury in acute renal failure are based on extensive
studies that identified cellular and molecular mechanisms of acute kidney injury. Despite …

Recent advances in acute kidney injury and its consequences... : Current Opinion in
Nephrology and Hypertension Recent advances in acute kidney injury and its …

Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and is a significant and frequent cause of morbidity and mortality …

The pathogenesis of acute kidney injury (AKI) is complex, involving such factors as
vasoconstriction, leukostasis, vascular congestion, cell death, and abnormal immune …